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- W2315563836 abstract "Recent advances in immunology and molecular biology revealed that majority of cases previously defined as true histiocytic neoplasias proved to be T-and B-cell lymphomas. We presented here several examples: Tr-lymphoma, malignant hisiocytosis-like B-cell lymphoma malignant histiocytosis presenting as lethal midline granuloma (MH-LMG). The MH-LMG is considered now to be a proliferation of natural killer cells by several investigators.We reviewed 1, 766 cases with malignant lymphoma and related diseases diagnosed at 17 hospitals situated in Osaka and Hyogo prefectures. On purely morphological grounds, thirty-five cases were selected as candidates of true histiocytic tumor, of these enzyme and immunohistochemical procedures were made on 23 cases. The results showed that 12 cases (52%) were of B-cell type, three cases (13%) T cell type, six cases (26%) true histiocytic type and two cases null cell type. Therefore frequency of cases with true histiocytic neoplasias among cases with malignant lymphoma and related conditions in Japan may be 0.5%." @default.
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- W2315563836 date "1990-01-01" @default.
- W2315563836 modified "2023-09-26" @default.
- W2315563836 title "Reevaluation of diseases with histiocytic proliferation." @default.
- W2315563836 doi "https://doi.org/10.3960/jslrt1961.30.301" @default.
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