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- W2315662225 abstract "Substituted piperazines and morpholines are valuable structural motifs in biologically active compounds, but are not easily prepared by contemporary cross-coupling approaches. In this report, we introduce SnAP reagents for the transformation of aldehydes into N-unprotected piperazines and morpholines. This approach offers simple, mild conditions compatible with aromatic, heteroaromatic, aliphatic, and glyoxylic aldehydes and provides mono- and disubstituted N-heterocycles in a single step." @default.
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- W2315662225 date "2014-02-06" @default.
- W2315662225 modified "2023-09-29" @default.
- W2315662225 title "SnAP Reagents for the Synthesis of Piperazines and Morpholines" @default.
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- W2315662225 doi "https://doi.org/10.1021/ol500210z" @default.
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