Matches in SemOpenAlex for { <https://semopenalex.org/work/W2315676324> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2315676324 endingPage "756" @default.
- W2315676324 startingPage "752" @default.
- W2315676324 abstract "A fragment analog, [D-Arg30]prothymosin alpha fragment 1-30, containing D-arginine in place of arginine residue at position 30 was synthesized by the liquid phase procedure and studied for immunological effect on the impaired blastogenic response of T-lymphocytes isolated from uremic patients after treatment of human serum. Deacetyl-thymosin alpha 1, a synthetic octaeicosapeptide corresponding to deacetyl-prothymosin alpha fragment 1-28, has restoration ability for the impaired blastogenic response of T-lymphocytes of uremic patients but is susceptible to proteolytic digestion. On the other hand, the fragment analog, [D-Arg30]prothymosin alpha fragment 1-30 retained activity and was shown to exhibit a high degree of stability when incubated in human serum. These results indicate that N-terminal acetylation and the introduction of D-residue into the C-terminal residue of prothymosin alpha fragment 1-30 increase resistance to proteolytic degradation by exopeptidases." @default.
- W2315676324 created "2016-06-24" @default.
- W2315676324 creator A5033271108 @default.
- W2315676324 creator A5080732842 @default.
- W2315676324 date "1991-01-01" @default.
- W2315676324 modified "2023-09-25" @default.
- W2315676324 title "Synthesis of an immunologically active fragment analog of prothymosin .ALPHA. with enhanced enzymatic stability." @default.
- W2315676324 cites W2322344246 @default.
- W2315676324 doi "https://doi.org/10.1248/cpb.39.752" @default.
- W2315676324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2070460" @default.
- W2315676324 hasPublicationYear "1991" @default.
- W2315676324 type Work @default.
- W2315676324 sameAs 2315676324 @default.
- W2315676324 citedByCount "2" @default.
- W2315676324 countsByYear W23156763242012 @default.
- W2315676324 countsByYear W23156763242013 @default.
- W2315676324 crossrefType "journal-article" @default.
- W2315676324 hasAuthorship W2315676324A5033271108 @default.
- W2315676324 hasAuthorship W2315676324A5080732842 @default.
- W2315676324 hasBestOaLocation W23156763241 @default.
- W2315676324 hasConcept C104317684 @default.
- W2315676324 hasConcept C119157956 @default.
- W2315676324 hasConcept C153911025 @default.
- W2315676324 hasConcept C159110408 @default.
- W2315676324 hasConcept C185592680 @default.
- W2315676324 hasConcept C2775944032 @default.
- W2315676324 hasConcept C2776451592 @default.
- W2315676324 hasConcept C2781338088 @default.
- W2315676324 hasConcept C49453240 @default.
- W2315676324 hasConcept C55493867 @default.
- W2315676324 hasConcept C64943373 @default.
- W2315676324 hasConcept C71240020 @default.
- W2315676324 hasConcept C71924100 @default.
- W2315676324 hasConcept C86803240 @default.
- W2315676324 hasConceptScore W2315676324C104317684 @default.
- W2315676324 hasConceptScore W2315676324C119157956 @default.
- W2315676324 hasConceptScore W2315676324C153911025 @default.
- W2315676324 hasConceptScore W2315676324C159110408 @default.
- W2315676324 hasConceptScore W2315676324C185592680 @default.
- W2315676324 hasConceptScore W2315676324C2775944032 @default.
- W2315676324 hasConceptScore W2315676324C2776451592 @default.
- W2315676324 hasConceptScore W2315676324C2781338088 @default.
- W2315676324 hasConceptScore W2315676324C49453240 @default.
- W2315676324 hasConceptScore W2315676324C55493867 @default.
- W2315676324 hasConceptScore W2315676324C64943373 @default.
- W2315676324 hasConceptScore W2315676324C71240020 @default.
- W2315676324 hasConceptScore W2315676324C71924100 @default.
- W2315676324 hasConceptScore W2315676324C86803240 @default.
- W2315676324 hasIssue "3" @default.
- W2315676324 hasLocation W23156763241 @default.
- W2315676324 hasLocation W23156763242 @default.
- W2315676324 hasOpenAccess W2315676324 @default.
- W2315676324 hasPrimaryLocation W23156763241 @default.
- W2315676324 hasRelatedWork W1981955989 @default.
- W2315676324 hasRelatedWork W2005010882 @default.
- W2315676324 hasRelatedWork W2009936943 @default.
- W2315676324 hasRelatedWork W2025294207 @default.
- W2315676324 hasRelatedWork W2027218880 @default.
- W2315676324 hasRelatedWork W2033349887 @default.
- W2315676324 hasRelatedWork W2120315712 @default.
- W2315676324 hasRelatedWork W2159081745 @default.
- W2315676324 hasRelatedWork W2383803137 @default.
- W2315676324 hasRelatedWork W2949461741 @default.
- W2315676324 hasVolume "39" @default.
- W2315676324 isParatext "false" @default.
- W2315676324 isRetracted "false" @default.
- W2315676324 magId "2315676324" @default.
- W2315676324 workType "article" @default.