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- W2315678799 abstract "目的：探讨血清白介素（interleukin,IL）-6、IL-8和降钙素原（procalcitonin,PCT）对急性重症胰腺炎（severe acute pancreatitis,SAP）继发感染的诊断价值.方法：按照是否继发感染将我院收治的85例SAP患者分为观察组（细菌感染）45例和对照组（非感染性SIRS）40例,观察两组患者血清IL-6、IL-8及PCT水平差异并比较IL-6、IL-8和PCT指标单独及联合诊断SAP继发感染的敏感性、特异性、阳性预测值、阴性预测值和准确性.结果：观察组患者血清IL-6、IL-8及PCT水平均显著高于对照组（135.02 pg/mL±99.11 pg/mL vs 60.06 pg/mL±40.19 pg/mL）、（107.19pg/mL±35.26 pg/mL vs 88.05 pg/mL±18.50pg/mL）、（2.58μg/L±1.35μg/L vs 1.48μg/L±0.65μg/L）,差异具有统计学意义（P〈0.01或P〈0.05）;单独诊断SAP继发感染PCT敏感性、特异性、阳性预测值、阴性预测值及准确性均最高（55.62%,93.36%,88.29%,70.02%,75.41%）,联合诊断SAP继发感染IL-6、IL-8和PCT联合特异性、阳性预测值及准确性最高（96.71%,94.42%,80.68%）.结论：IL-6、IL-8和PCT均为诊断SAP继发感染的重要指标,其中单独诊断PCT鉴别能力最强,3项指标联合诊断特异性和准确率最高." @default.
- W2315678799 created "2016-06-24" @default.
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- W2315678799 date "2014-01-01" @default.
- W2315678799 modified "2023-09-26" @default.
- W2315678799 title "Role of serum IL-6, IL-8 and procalcitonin in diagnosis of secondary infection in severe acute pancreatitis" @default.
- W2315678799 doi "https://doi.org/10.11569/wcjd.v22.i16.2343" @default.
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