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- W2315679350 abstract "[14C]Guanidine was observed in the urine after subcutaneous administration to rats of l-[guanidino-14C]arginine or l-[guanidino-14C]canavanine. [14C]Hydroxyguanidine was additionally detected in the urine after injection of dl-[guanidino-14C]canavanine. These 14C metabolites were characterized by high-voltage electrophoresis and paper chromatography, by enzymatic conversion of [14C]hydroxyguanidine to [14C]guanidine, and by repeated recrystallization of isolated urinary [14C]guanidine as the picrate salt with no significant loss of specific activity. These experiments demonstrate that both l-arginine and l-canavanine can serve as precursors of guanidine in the rat." @default.
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- W2315679350 date "1979-10-01" @default.
- W2315679350 modified "2023-09-25" @default.
- W2315679350 title "Studies on the metabolism of guanidine compounds in mammals" @default.
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- W2315679350 doi "https://doi.org/10.1016/0003-9861(79)90227-3" @default.
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