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- W2315915412 abstract "Background: During the 2009 pandemic of influenza A (H1N1), many studies reported estimates of the reproduction number from outbreak data. Since then, seroprevalence studies have been conducted in a number of countries to assess the proportion of the population that was infected in the first wave of the pandemic. Methods: Here, we collate the reproduction number estimates, and use mathematical models to reconcile these with serosurvey data. Results: Most estimates of the reproduction number from outbreaks are in the range of 1.0–2.0, whereas mean estimates calculated from seroprevalence data range from 1.14 to 1.36. Age-specific analysis of these data suggests that the reproduction number for children was approximately 1.6, whereas the reproduction numbers for adults >25 years of age was less than 1.0. Conclusion: The difference between age-groups may help to explain high estimates of the reproduction number from outbreaks involving a large proportion of child cases." @default.
- W2315915412 created "2016-06-24" @default.
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- W2315915412 date "2012-01-01" @default.
- W2315915412 modified "2023-10-09" @default.
- W2315915412 title "Pandemic Influenza H1N1" @default.
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- W2315915412 doi "https://doi.org/10.1097/ede.0b013e31823a44a5" @default.
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