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- W2315949319 abstract "Objective: To report apathetic and hypoactive depression caused by olanzapine. Case Summary: A 29-year-old white man and a 29-year-old white woman developed apathy, hypoactivity, blunted affect, depressed mood, and other depressive symptoms while taking olanzapine. Both showed a distinctly abnormal appearance. Clinicians attributed these symptoms to psychiatric illness, but the symptoms disappeared rapidly after drug discontinuation or dose decrease. Discussion: The only previous report of depression from olanzapine involved a medication interaction with fluoxetine. Another report described olanzapine-induced orbital-frontal syndrome, with childlike oversimplicity. If such symptoms are observed, the discontinuation of olanzapine is recommended. Conclusions: These observations suggest additional cautions when olanzapine is used outside of schizophrenia." @default.
- W2315949319 created "2016-06-24" @default.
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- W2315949319 date "2002-11-01" @default.
- W2315949319 modified "2023-09-28" @default.
- W2315949319 title "Olanzapine-Induced Depression" @default.
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- W2315949319 doi "https://doi.org/10.1177/875512250201800606" @default.
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