Matches in SemOpenAlex for { <https://semopenalex.org/work/W2315981876> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2315981876 endingPage "1872" @default.
- W2315981876 startingPage "1862" @default.
- W2315981876 abstract "This study investigated the toxic implication of Febi Super Bitters in Male Wistar rats because of upsurge in its usage for therapeutic reasons. Eighteen rats, with an average weight of 86.2 +/- 4.43 g, were randomly distributed into three equal groups of six rats per group. The rats were acclimatized for 14 days and 0.308 and 0.462 mL kg(-1) b.wt. of Febi super bitters were administered daily to groups B and C, respectively for 56 days, while group A received distilled water. The toxicity of the herbal bitter was assessed by determining the activities of Lactate Dehydrogenate (LDH), Alkaline Phosphatase (ALP) and Acid Phosphatase (ACP) in the liver, kidney, small intestine, heart, brain, lungs, spleen, serum and histological studies on the organs. The activities of LDH were significantly reduced (p < 0.05) in the liver, small intestine and lung, while it increased significantly (p < 0.05) in the brain and serum. ALP activities decreased significantly (p < 0.05) in the liver, kidney, small intestine and heart but increased (p < 0.05) in brain, spleen and serum. ACP activities in the liver and kidney were decreased (p<0.05) and increased significantly (p < 0.05) in the spleen and serum. Increases were significantly recorded in serum total bilirubin, unconjugated bilirubin, total protein and globulin, while reductions were recorded in the conjugated bilirubin and A/G (p < 0.05). Histoarchitecture of the lungs, spleen and small intestine revealed marked cellular distortions. In the light of these findings, the habitual consumption of Febi super bitters is not recommended as it has underlined toxicity in some vital internal organs." @default.
- W2315981876 created "2016-06-24" @default.
- W2315981876 creator A5020713440 @default.
- W2315981876 creator A5023968174 @default.
- W2315981876 creator A5051137431 @default.
- W2315981876 creator A5052679353 @default.
- W2315981876 date "2013-12-01" @default.
- W2315981876 modified "2023-09-25" @default.
- W2315981876 title "Repeated Oral Administration of Febi Super Bitters Correlated with Some Tissue Toxicity in Male Wistar Rat" @default.
- W2315981876 cites W2007991942 @default.
- W2315981876 cites W2024789677 @default.
- W2315981876 cites W2029761949 @default.
- W2315981876 cites W2033089404 @default.
- W2315981876 cites W2057930190 @default.
- W2315981876 cites W2084437748 @default.
- W2315981876 cites W2091835032 @default.
- W2315981876 cites W2123320697 @default.
- W2315981876 cites W2155853588 @default.
- W2315981876 doi "https://doi.org/10.3923/pjbs.2013.1862.1872" @default.
- W2315981876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24517001" @default.
- W2315981876 hasPublicationYear "2013" @default.
- W2315981876 type Work @default.
- W2315981876 sameAs 2315981876 @default.
- W2315981876 citedByCount "0" @default.
- W2315981876 crossrefType "journal-article" @default.
- W2315981876 hasAuthorship W2315981876A5020713440 @default.
- W2315981876 hasAuthorship W2315981876A5023968174 @default.
- W2315981876 hasAuthorship W2315981876A5051137431 @default.
- W2315981876 hasAuthorship W2315981876A5052679353 @default.
- W2315981876 hasConcept C126322002 @default.
- W2315981876 hasConcept C134018914 @default.
- W2315981876 hasConcept C160160445 @default.
- W2315981876 hasConcept C181199279 @default.
- W2315981876 hasConcept C185592680 @default.
- W2315981876 hasConcept C2776366702 @default.
- W2315981876 hasConcept C2777513400 @default.
- W2315981876 hasConcept C2777714996 @default.
- W2315981876 hasConcept C2777882243 @default.
- W2315981876 hasConcept C2779429693 @default.
- W2315981876 hasConcept C2780091579 @default.
- W2315981876 hasConcept C2780931953 @default.
- W2315981876 hasConcept C29730261 @default.
- W2315981876 hasConcept C43617362 @default.
- W2315981876 hasConcept C55493867 @default.
- W2315981876 hasConcept C71924100 @default.
- W2315981876 hasConcept C81358767 @default.
- W2315981876 hasConceptScore W2315981876C126322002 @default.
- W2315981876 hasConceptScore W2315981876C134018914 @default.
- W2315981876 hasConceptScore W2315981876C160160445 @default.
- W2315981876 hasConceptScore W2315981876C181199279 @default.
- W2315981876 hasConceptScore W2315981876C185592680 @default.
- W2315981876 hasConceptScore W2315981876C2776366702 @default.
- W2315981876 hasConceptScore W2315981876C2777513400 @default.
- W2315981876 hasConceptScore W2315981876C2777714996 @default.
- W2315981876 hasConceptScore W2315981876C2777882243 @default.
- W2315981876 hasConceptScore W2315981876C2779429693 @default.
- W2315981876 hasConceptScore W2315981876C2780091579 @default.
- W2315981876 hasConceptScore W2315981876C2780931953 @default.
- W2315981876 hasConceptScore W2315981876C29730261 @default.
- W2315981876 hasConceptScore W2315981876C43617362 @default.
- W2315981876 hasConceptScore W2315981876C55493867 @default.
- W2315981876 hasConceptScore W2315981876C71924100 @default.
- W2315981876 hasConceptScore W2315981876C81358767 @default.
- W2315981876 hasIssue "24" @default.
- W2315981876 hasLocation W23159818761 @default.
- W2315981876 hasLocation W23159818762 @default.
- W2315981876 hasOpenAccess W2315981876 @default.
- W2315981876 hasPrimaryLocation W23159818761 @default.
- W2315981876 hasRelatedWork W2025404809 @default.
- W2315981876 hasRelatedWork W2042033030 @default.
- W2315981876 hasRelatedWork W2070511355 @default.
- W2315981876 hasRelatedWork W2074728525 @default.
- W2315981876 hasRelatedWork W2082456910 @default.
- W2315981876 hasRelatedWork W2127085070 @default.
- W2315981876 hasRelatedWork W2400445066 @default.
- W2315981876 hasRelatedWork W2748952813 @default.
- W2315981876 hasRelatedWork W3024240219 @default.
- W2315981876 hasRelatedWork W4247840798 @default.
- W2315981876 hasVolume "16" @default.
- W2315981876 isParatext "false" @default.
- W2315981876 isRetracted "false" @default.
- W2315981876 magId "2315981876" @default.
- W2315981876 workType "article" @default.