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- W2316021811 abstract "Background and Goal of Study: Delayed cerebral ischaemia (DCI) is a major cause of morbidity & mortality after aneurysmal subarachnoid haemorrhage (SAH). Current evidence for use of “triple H” therapy (THT) to manage DCI is limited and based on small studies or case series [1]. Recent consensus guidance has been published [2]. The aim of this study is to create a snapshot of the application of THT in the management of DCI in the UK. Methods: A peer-reviewed web-based survey was sent to the lead clinician at each of the UK's 31 neurocritical care units. Results: There was a 71% response rate. Median (range) annual number of SAH patients treated in each unit is 88 (10–250). 95% use THT for treatment & 23% for prophylaxis of DCI, with 50% of units having a THT protocol. 100% induce hypertension, with SBP & MAP targeted equally, 65% hypervolaemia & 30% haemodilution. 57% use saline and 24% Hartmann's solution as fluid replacement. Norepinephrine is the most widely used vasopressor. Target haemoglobin is >9 g/dl in 94% of units. Conclusion: Treatment of DCI is relatively uniform in the UK, with almost universal use of induced hypertension being in keeping with recent guidance [1]. There is variation in the cardiovascular target & choice of fluid replacement. Reference: Diringer, et al. Neurocrit Care (2011)15:211-240 Meyer, et al. Neurocrit Care (2011)14:24-36" @default.
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- W2316021811 date "2012-02-01" @default.
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- W2316021811 title "A27 Contemporary Practice of Triple H Therapy Management for Aneurysmal Subarachnoid Haemorrhage in the UK" @default.
- W2316021811 doi "https://doi.org/10.1097/01.eja.0000412473.22934.02" @default.
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