FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316093669> ?p ?o ?g. }

• W2316093669 abstract "Objective: To explore the association of nocturnal limb movements (LMs) and sleep quality with cerebral white matter hyperintensities (WMH). Background Nocturnal LMs are associated with transient but significant increases in night-time blood pressure and autonomic hyperactivity; emerging evidence suggests a link with vascular disease. While obstructive sleep apnea is linked with WMH, the relationship between nocturnal LMs and WMH remains to be clarified. Design/Methods: Patients evaluated in a tertiary care behavioral neurology clinic were assessed with polysomnography for various sleep problems. Polysomnography was scored according to criteria from the American Academy of Sleep Medicine. WMH were rated using the Age Related White Matter Changes Score (ARWMC) from FLAIR MRI. Polysomnographic (transformed where necessary) and ARWMC data were compared using Pearson correlations. Results: Forty-five participants were assessed (69% male, mean age 64 years) and vascular risk factors were as follows: hypertension (27%), hyperlipidemia (18%) and diabetes (9%). Prior cerebrovascular disease (7%), obstructive sleep apnea (49%) and restless legs syndrome (33%) were also present. The mean ARWMC score was 3.84 (range 0-25, standard deviation 4.73). When controlling for hypertension, the total ARWMC score was correlated with total LMs per hour of sleep (r=0.66, p=0.01). There were no differences in the ARWMC score between hemispheres, but more LMs were noted on the left side (66.3 vs. 24.1, p Conclusions: LM counts strongly correlated with the presence of WMH. In addition, sleep efficiency was negatively correlated with WMH. In keeping with developing evidence, our findings suggest that nocturnal LMs associated with poor quality sleep may contribute to episodes of nocturnal hypertension, which have been implicated in the development of WMH, even after controlling for the presence of daytime hypertension. Supported by: Dr. Mark Boulos is supported by a Focus on Stroke Research Fellowship, which is funded by the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Canada, and the Canadian Stroke Network. Disclosure: Dr. Boulos has nothing to disclose. Dr. Pettersen has nothing to disclose. Dr. Jewell has nothing to disclose. Dr. Black has received personal compensation for activities with Novartis Pharmaceuticals, Pfizer, GlaxoSmithKline, Roche Pharmaceuticals, and Bristol-Myers Squibb. Dr. Black has received research support from Novartis Pharmaceuticals, Pfizer, Roche, and GlaxoSmithKline. Dr. Murray has received personal compensation for activities with Pfizer and Valeant as a consultant." @default.
• W2316093669 created "2016-06-24" @default.
• W2316093669 creator A5004853845 @default.
• W2316093669 creator A5040635626 @default.
• W2316093669 creator A5041527352 @default.
• W2316093669 creator A5051480473 @default.
• W2316093669 creator A5086963249 @default.
• W2316093669 date "2012-04-22" @default.
• W2316093669 modified "2023-09-27" @default.
• W2316093669 title "Nocturnal Limb Movements Are Correlated with Cerebral White Matter Hyperintensities (P05.001)" @default.
• W2316093669 doi "https://doi.org/10.1212/wnl.78.1_meetingabstracts.p05.001" @default.
• W2316093669 hasPublicationYear "2012" @default.
• W2316093669 type Work @default.
• W2316093669 sameAs 2316093669 @default.
• W2316093669 citedByCount "0" @default.
• W2316093669 crossrefType "journal-article" @default.
• W2316093669 hasAuthorship W2316093669A5004853845 @default.
• W2316093669 hasAuthorship W2316093669A5040635626 @default.
• W2316093669 hasAuthorship W2316093669A5041527352 @default.
• W2316093669 hasAuthorship W2316093669A5051480473 @default.
• W2316093669 hasAuthorship W2316093669A5086963249 @default.
• W2316093669 hasConcept C118552586 @default.
• W2316093669 hasConcept C126322002 @default.
• W2316093669 hasConcept C126838900 @default.
• W2316093669 hasConcept C143409427 @default.
• W2316093669 hasConcept C146638467 @default.
• W2316093669 hasConcept C15744967 @default.
• W2316093669 hasConcept C164705383 @default.
• W2316093669 hasConcept C16568411 @default.
• W2316093669 hasConcept C2776006263 @default.
• W2316093669 hasConcept C2778096610 @default.
• W2316093669 hasConcept C2778205975 @default.
• W2316093669 hasConcept C2779134260 @default.
• W2316093669 hasConcept C2781326671 @default.
• W2316093669 hasConcept C71924100 @default.
• W2316093669 hasConceptScore W2316093669C118552586 @default.
• W2316093669 hasConceptScore W2316093669C126322002 @default.
• W2316093669 hasConceptScore W2316093669C126838900 @default.
• W2316093669 hasConceptScore W2316093669C143409427 @default.
• W2316093669 hasConceptScore W2316093669C146638467 @default.
• W2316093669 hasConceptScore W2316093669C15744967 @default.
• W2316093669 hasConceptScore W2316093669C164705383 @default.
• W2316093669 hasConceptScore W2316093669C16568411 @default.
• W2316093669 hasConceptScore W2316093669C2776006263 @default.
• W2316093669 hasConceptScore W2316093669C2778096610 @default.
• W2316093669 hasConceptScore W2316093669C2778205975 @default.
• W2316093669 hasConceptScore W2316093669C2779134260 @default.
• W2316093669 hasConceptScore W2316093669C2781326671 @default.
• W2316093669 hasConceptScore W2316093669C71924100 @default.
• W2316093669 hasLocation W23160936691 @default.
• W2316093669 hasOpenAccess W2316093669 @default.
• W2316093669 hasPrimaryLocation W23160936691 @default.
• W2316093669 hasRelatedWork W1564027793 @default.
• W2316093669 hasRelatedWork W1577690094 @default.
• W2316093669 hasRelatedWork W1633756788 @default.
• W2316093669 hasRelatedWork W1995169865 @default.
• W2316093669 hasRelatedWork W2054302819 @default.
• W2316093669 hasRelatedWork W2125374665 @default.
• W2316093669 hasRelatedWork W2319178093 @default.
• W2316093669 hasRelatedWork W2336148229 @default.
• W2316093669 hasRelatedWork W2546702957 @default.
• W2316093669 hasRelatedWork W2563190839 @default.
• W2316093669 hasRelatedWork W2564148900 @default.
• W2316093669 hasRelatedWork W2677052597 @default.
• W2316093669 hasRelatedWork W2747993187 @default.
• W2316093669 hasRelatedWork W2775255401 @default.
• W2316093669 hasRelatedWork W2806279898 @default.
• W2316093669 hasRelatedWork W2808532502 @default.
• W2316093669 hasRelatedWork W2945432560 @default.
• W2316093669 hasRelatedWork W3092267302 @default.
• W2316093669 hasRelatedWork W3164786594 @default.
• W2316093669 hasRelatedWork W3198231074 @default.
• W2316093669 isParatext "false" @default.
• W2316093669 isRetracted "false" @default.
• W2316093669 magId "2316093669" @default.
• W2316093669 workType "article" @default.