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- W2316193755 abstract "When spinal cord injury (SCI) occurs, injured cells must survive and regenerate to close gaps caused by the injury and to create functional motor units. After peripheral nerve injury, Wallerian degeneration in the distal nerve stump creates a neurotrophic and growth-supportive environment for injured neurons and axons via Schwann cells and secreted cytokines/neurotrophins. In both SCI and peripheral nerve injury, injured motor and sensory neurons must regenerate axons, eventually reaching and reinnervating target tissue (SDC Figure 1, http://links.lww.com/BRS/B116). This process is often unsuccessful after SCI, and the highly complex anatomy of branching axons and nerves in the peripheral nervous system leads to slow recovery of function, even with careful and appropriate techniques." @default.
- W2316193755 created "2016-06-24" @default.
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- W2316193755 date "2016-04-01" @default.
- W2316193755 modified "2023-09-27" @default.
- W2316193755 title "Transforming Growth Factor-β Promotes Axonal Regeneration After Chronic Nerve Injury" @default.
- W2316193755 doi "https://doi.org/10.1097/brs.0000000000001435" @default.
- W2316193755 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27015069" @default.
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