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• W2316201616 abstract "Two total syntheses of the indolo[2,3-a]quinolizinium cation have been accomplished through the application of two ring-closing metathesis reactions to form the pyridinium ring. One of these approaches provides the tetracyclic cation in only five steps from commercially available harmane. Fluorescence-based thermal denaturation experiments, as well as spectrofluorimetric titration, circular dichroism measurements, and theoretical simulations, showed a consistent DNA-binding capacity by intercalation with a marked preference for AT-rich sequences." @default.
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• W2316201616 date "2014-06-18" @default.
• W2316201616 modified "2023-10-18" @default.
• W2316201616 title "Efficient Synthesis of an Indoloquinolizinium Alkaloid Selective DNA-Binder by Ring-Closing Metathesis" @default.
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• W2316201616 doi "https://doi.org/10.1021/ol5013668" @default.
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• W2316201616 hasPublicationYear "2014" @default.
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