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• W2316226741 abstract "Five novel perhydrobenzannulated 5,5-spiroketal sesquiterpenes, namely, pleurospiroketals A-E (1-5), were isolated from the culture of the edible mushroom Pleurotus cornucopiae. Pleurospiroketals D (4) and E (5) were obtained as an isomeric mixture with a ratio of 5:4. Their structures were established by NMR, X-ray single-crystal diffraction, and CD data analysis. Pleurospiroketals A-E (1-5) are sesquiterpenoids with a unique benzannulated 5,5-spiroketal skeleton. Compounds 1-3 showed inhibitory activity against nitric oxide production in lipopolysaccharide-activated macrophages with IC(50) values of 6.8, 12.6, and 20.8 μM, respectively." @default.
• W2316226741 created "2016-06-24" @default.
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• W2316226741 date "2013-01-08" @default.
• W2316226741 modified "2023-09-26" @default.
• W2316226741 title "Pleurospiroketals A–E, Perhydrobenzannulated 5,5-Spiroketal Sesquiterpenes from the Edible Mushroom <i>Pleurotus cornucopia</i>e" @default.
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• W2316226741 doi "https://doi.org/10.1021/np3006524" @default.
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