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- W2316235946 abstract "Clinical outcomes and problems were studied in 18 patients of acute cerebral infarction who underwent thrombolytic therapy by intravenous administration of rt-PA started within 3 hours from onset. 10 patients (55.6%) resulted in modified Rankin Scale 0 or 1 at 3 months after onset. However, the diagnosis of ischemic early sign on the CT image was sometimes difficult, the diagnosis of high intensity area on the diffusion wighted image of MRI was easy. Before the intravenous administration of rt-PA, any ischemic early sign was detected in 3 patients on the CT image, but any high intensity area was detected in 16 patients on the diffusion wighted image of MRI. 8 patients showed neurological improvement during the intravenous administration of rt-PA, but 4 patients showed neurological deterioration again after the intravenous administration of rt-PA. The clinical outcome was poor in patients with main arterial occlusion on MRA such as internal carotid artery, basilar artery or M1 of middle cerebral artery occlusion. The intravenous administration of rt-PA is effective therapy for acute cerebral infarction, but some problems are considered to be resolved for patients' better outcome." @default.
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- W2316235946 date "2006-01-01" @default.
- W2316235946 modified "2023-09-30" @default.
- W2316235946 title "Clinical outcomes and problems in the acute thrombolytic therapy by intravenous administration of rt-PA" @default.
- W2316235946 doi "https://doi.org/10.3995/jstroke.28.661" @default.
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