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• W2316360035 abstract "Solitonlike propagating modes have been proposed for excitable tissue, but have never been measured in cardiac tissue. In this study, we simulate an experimental protocol to elicit these propagating unstable wavelets (PUWs) in a detailed three-dimensional ventricular wedge preparation. PUWs appear as fixed-shape wavelets that propagate only in the direction of cardiac fibers, with conduction velocity approximately $40%$ slower than normal action potential excitation. We investigate their properties, demonstrating that PUWs are not true solitons. The range of stimuli for which PUWs were elicited was very narrow (several orders of magnitude lower than the stimulus strength itself), but increased with reduced sodium conductance and reduced coupling in nonlongitudinal directions. We show that the phenomenon does not depend on the particular membrane representation used or the shape of the stimulating electrode." @default.
• W2316360035 created "2016-06-24" @default.
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• W2316360035 date "2012-01-11" @default.
• W2316360035 modified "2023-09-27" @default.
• W2316360035 title "Propagating unstable wavelets in cardiac tissue" @default.
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• W2316360035 doi "https://doi.org/10.1103/physreve.85.011909" @default.
• W2316360035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22400593" @default.
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