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- W2316392934 abstract "In this work we present work on a novel amorphous calcium phosphate nanoparticle system for use in bioimaging and drug delivery applications. The system, by virtue of its synthesis, can be made to encapsulate and protect any number of molecules that are not suitable for biological applications on their own; for example, medication that is poorly soluble inaqueous solution can be encapsulated for delivery, or fragile optical molecules can be encapsulated to protect them from the local environment. We have encapsulated the near-infrared dye indocyanine green, which has bene�ficial properties for optical imaging (low biotoxicity, absorption and emission at a minimum of tissue absorption). There are two original works presented in this thesis. The fi�rst describes the measurement of the quantum yield of the indocyanine green-doped nanoparticles, as well as the development of a theoretical methodto extract the molecular quantum yield of a fluorophore encapsulated in a dielectric spherefrom eff�ective quantum yield measurements of nanoparticle dispersions in solution. The secondwork is an application of diff�use scattering theory to the problem of light propagationin biological tissue; speci�fically, the limits on penetration depth for photodynamic therapyand bioimaging." @default.
- W2316392934 created "2016-06-24" @default.
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- W2316392934 date "2009-04-10" @default.
- W2316392934 modified "2023-09-23" @default.
- W2316392934 title "Interaction of Light with Dye-Doped Calcium Phosphate Nanoparticles" @default.
- W2316392934 hasPublicationYear "2009" @default.
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