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- W2316442008 abstract "Carbohydrates play a central role in the body, but synthesizing them for drug-design studies or functional studies is notoriously difficult. That's what motivated chemistry professor Chi- Huey Wong and coworkers at Scripps Research Institute, La Jolla, Calif., to develop a technique for synthesizing oligosaccharides more easily—by computer [ J. Am. Chew. Soc., 121, 734 (1999)]. This is the first time that a personal computer has been used in a systematic manner to guide the synthesis of carbohydrates by researchers who may or may not know that much about carbohydrate synthesis, Wong says. We simplified the synthesis of carbohydrates by developing a program called OptiMer. Scripps has applied for a patent on the synthetic system and Wong believes it eventually will be commercialized. If it is, scientists would be able to buy building-block reagents designed by Wong's group and use OptiMer to make the carbohydrates they want. You can create a library of oligosaccharides one-by-one, ..." @default.
- W2316442008 created "2016-06-24" @default.
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- W2316442008 date "1999-03-22" @default.
- W2316442008 modified "2023-09-27" @default.
- W2316442008 title "Oligosaccharides Made To Order" @default.
- W2316442008 doi "https://doi.org/10.1021/cen-v077n012.p030" @default.
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