FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316447103> ?p ?o ?g. }

• W2316447103 endingPage "328" @default.
• W2316447103 startingPage "321" @default.
• W2316447103 abstract "The human immunodeficiency virus (HIV) infection results in biochemical and vascular dysfunctions. The highly active antiretroviral therapy (HAART) markedly reduces mortality and opportunistic diseases associated with acquired immunodeficiency syndrome (AIDS). This increased survival time predisposes the development of cardiovascular diseases. Platelets present purinergic system ectoenzymes such as E-NTPDase, E-5′-nucleotidase and E-ADA on its surface. In view of this, the aim of this study was to evaluate the activity of these ectoenzymes in platelets as well as the platelet aggregation and lipid profile of patients with HIV infection and also patients receiving HAART. The results showed an increase in the E-NTPDase activity for ATP hydrolysis in the HIV group compared with the control group and the HIV/HAART group. When assessing the activity E-NTPDase hydrolysis to ADP, the results revealed an increase in activity in the HIV group when compared to the control group, and a decrease in activity when in the HIV/HAART group when compared to the control and HIV groups. The activity of E-5′-nucleotidase revealed an increase in AMP hydrolysis in the HIV group, as the results from control and HIV/HAART groups showed no statistical difference. Regarding the E-ADA activity, the HIV and HIV/HAART groups revealed a decreased deamination of adenosine when compared with the control group. Furthermore, we observed an increased platelet aggregation of HIV/HAART group compared with the control group. Thus, our results suggest that antiretroviral treatment against HIV has a significant effect on the activity of purinergic system ectoenzymes demonstrating that thromboregulation is involved in the process." @default.
• W2316447103 created "2016-06-24" @default.
• W2316447103 creator A5006149550 @default.
• W2316447103 creator A5020967076 @default.
• W2316447103 creator A5043048209 @default.
• W2316447103 creator A5048325372 @default.
• W2316447103 creator A5067657116 @default.
• W2316447103 creator A5070950022 @default.
• W2316447103 creator A5072999640 @default.
• W2316447103 creator A5076920841 @default.
• W2316447103 creator A5082375702 @default.
• W2316447103 creator A5082527789 @default.
• W2316447103 creator A5082738366 @default.
• W2316447103 creator A5087051080 @default.
• W2316447103 date "2016-04-01" @default.
• W2316447103 modified "2023-10-17" @default.
• W2316447103 title "Effect of antiretroviral therapy in thromboregulation through the hydrolysis of adenine nucleotides in platelets of HIV patients" @default.
• W2316447103 cites W1619104716 @default.
• W2316447103 cites W1964510458 @default.
• W2316447103 cites W1966029386 @default.
• W2316447103 cites W1967412131 @default.
• W2316447103 cites W1970079470 @default.
• W2316447103 cites W1972709291 @default.
• W2316447103 cites W1975167252 @default.
• W2316447103 cites W1980247527 @default.
• W2316447103 cites W1983253822 @default.
• W2316447103 cites W1983745441 @default.
• W2316447103 cites W1985407729 @default.
• W2316447103 cites W1989576769 @default.
• W2316447103 cites W2005858175 @default.
• W2316447103 cites W2014951192 @default.
• W2316447103 cites W2025158687 @default.
• W2316447103 cites W2025481552 @default.
• W2316447103 cites W2028074917 @default.
• W2316447103 cites W2028124524 @default.
• W2316447103 cites W2032002843 @default.
• W2316447103 cites W2043423540 @default.
• W2316447103 cites W2046020531 @default.
• W2316447103 cites W2048898625 @default.
• W2316447103 cites W2058021232 @default.
• W2316447103 cites W2060044770 @default.
• W2316447103 cites W2063843920 @default.
• W2316447103 cites W2064433635 @default.
• W2316447103 cites W2067426910 @default.
• W2316447103 cites W2073340180 @default.
• W2316447103 cites W2077930885 @default.
• W2316447103 cites W2085442547 @default.
• W2316447103 cites W2094401395 @default.
• W2316447103 cites W2095336107 @default.
• W2316447103 cites W2095988220 @default.
• W2316447103 cites W2097649959 @default.
• W2316447103 cites W2102110536 @default.
• W2316447103 cites W2121511741 @default.
• W2316447103 cites W2138599948 @default.
• W2316447103 cites W2143118714 @default.
• W2316447103 cites W2143796803 @default.
• W2316447103 cites W2161396736 @default.
• W2316447103 cites W2167539001 @default.
• W2316447103 cites W4293247451 @default.
• W2316447103 doi "https://doi.org/10.1016/j.biopha.2016.02.008" @default.
• W2316447103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27044844" @default.
• W2316447103 hasPublicationYear "2016" @default.
• W2316447103 type Work @default.
• W2316447103 sameAs 2316447103 @default.
• W2316447103 citedByCount "9" @default.
• W2316447103 countsByYear W23164471032017 @default.
• W2316447103 countsByYear W23164471032018 @default.
• W2316447103 countsByYear W23164471032019 @default.
• W2316447103 countsByYear W23164471032021 @default.
• W2316447103 countsByYear W23164471032022 @default.
• W2316447103 countsByYear W23164471032023 @default.
• W2316447103 crossrefType "journal-article" @default.
• W2316447103 hasAuthorship W2316447103A5006149550 @default.
• W2316447103 hasAuthorship W2316447103A5020967076 @default.
• W2316447103 hasAuthorship W2316447103A5043048209 @default.
• W2316447103 hasAuthorship W2316447103A5048325372 @default.
• W2316447103 hasAuthorship W2316447103A5067657116 @default.
• W2316447103 hasAuthorship W2316447103A5070950022 @default.
• W2316447103 hasAuthorship W2316447103A5072999640 @default.
• W2316447103 hasAuthorship W2316447103A5076920841 @default.
• W2316447103 hasAuthorship W2316447103A5082375702 @default.
• W2316447103 hasAuthorship W2316447103A5082527789 @default.
• W2316447103 hasAuthorship W2316447103A5082738366 @default.
• W2316447103 hasAuthorship W2316447103A5087051080 @default.
• W2316447103 hasConcept C126322002 @default.
• W2316447103 hasConcept C18880352 @default.
• W2316447103 hasConcept C203014093 @default.
• W2316447103 hasConcept C2776991684 @default.
• W2316447103 hasConcept C2777913276 @default.
• W2316447103 hasConcept C3013748606 @default.
• W2316447103 hasConcept C34628245 @default.
• W2316447103 hasConcept C71924100 @default.
• W2316447103 hasConcept C89560881 @default.
• W2316447103 hasConcept C90924648 @default.
• W2316447103 hasConceptScore W2316447103C126322002 @default.
• W2316447103 hasConceptScore W2316447103C18880352 @default.
• W2316447103 hasConceptScore W2316447103C203014093 @default.
• W2316447103 hasConceptScore W2316447103C2776991684 @default.

• next