FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316452615> ?p ?o ?g. }

• W2316452615 endingPage "96" @default.
• W2316452615 startingPage "89" @default.
• W2316452615 abstract "Magnetic resonance imaging (MRI) using magnetic nanoparticles has been used to diagnose vascular diseases as well as to monitor transplanted cells and tissues. In this study, we synthesized magnetic iron oxide nanoparticles (TMADM-03), electrically charged by the presence of a cationic end-group substitution of dextran, and observed these nanoparticles inside three-dimensional models of HepG2 spheroids, which mimic tissues. Patterned cell array glass disks were prepared to visualize the presence of TMADM-03 uptaken by HepG2 spheroids using transmission electron microscopy (TEM). The HepG2 cells (2 × 10(5) cells) were inoculated onto Cell-able™ 12-well plates. After 48 h of culture, the cells were incubated with 75 µg Fe/ml TMADM-03 in culture medium for 24 h. To investigate the cellular function of the HepG2 spheroids, the albumin secretion was evaluated by an ELISA. The albumin secretion after incubation for 24 h was reduced compared with the secretion prior to the addition of TMADM-03. TEM image samples were prepared in a planar direction or a vertical direction to the HepG2 spheroids on patterned cell array glass disks. The incorporation of TMADM-03 inside the HepG2 spheroids was confirmed. In addition, TMADM-03 could be observed in the deeper layers of the spheroids, and this was localized in the lysosomes. These data suggest that the novel magnetic iron oxide nanoparticles invade three-dimensional HepG2 spheroids." @default.
• W2316452615 created "2016-06-24" @default.
• W2316452615 creator A5000633937 @default.
• W2316452615 creator A5008549101 @default.
• W2316452615 creator A5021126434 @default.
• W2316452615 creator A5032413419 @default.
• W2316452615 creator A5039463412 @default.
• W2316452615 creator A5057180752 @default.
• W2316452615 creator A5057379050 @default.
• W2316452615 creator A5058589470 @default.
• W2316452615 creator A5059096605 @default.
• W2316452615 creator A5067197714 @default.
• W2316452615 creator A5067876698 @default.
• W2316452615 creator A5077738482 @default.
• W2316452615 creator A5088151988 @default.
• W2316452615 date "2013-08-01" @default.
• W2316452615 modified "2023-10-05" @default.
• W2316452615 title "Observation of Positively Charged Magnetic Nanoparticles inside HepG2 Spheroids Using Electron Microscopy" @default.
• W2316452615 cites W1510613202 @default.
• W2316452615 cites W1971496706 @default.
• W2316452615 cites W1980030500 @default.
• W2316452615 cites W1980720314 @default.
• W2316452615 cites W1981517394 @default.
• W2316452615 cites W2006919788 @default.
• W2316452615 cites W2016278775 @default.
• W2316452615 cites W2028333440 @default.
• W2316452615 cites W2031565650 @default.
• W2316452615 cites W2033778299 @default.
• W2316452615 cites W2037149132 @default.
• W2316452615 cites W2047657486 @default.
• W2316452615 cites W2054623041 @default.
• W2316452615 cites W2069928673 @default.
• W2316452615 cites W2081854856 @default.
• W2316452615 cites W2085087023 @default.
• W2316452615 cites W2101574424 @default.
• W2316452615 cites W2115170749 @default.
• W2316452615 cites W2126491115 @default.
• W2316452615 cites W2164324123 @default.
• W2316452615 cites W2313463263 @default.
• W2316452615 cites W2328776985 @default.
• W2316452615 cites W2328786770 @default.
• W2316452615 cites W2396726629 @default.
• W2316452615 cites W2464939828 @default.
• W2316452615 cites W2498459622 @default.
• W2316452615 doi "https://doi.org/10.3727/215517913x666530" @default.
• W2316452615 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4733861" @default.
• W2316452615 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26858871" @default.
• W2316452615 hasPublicationYear "2013" @default.
• W2316452615 type Work @default.
• W2316452615 sameAs 2316452615 @default.
• W2316452615 citedByCount "10" @default.
• W2316452615 countsByYear W23164526152015 @default.
• W2316452615 countsByYear W23164526152017 @default.
• W2316452615 countsByYear W23164526152018 @default.
• W2316452615 countsByYear W23164526152019 @default.
• W2316452615 countsByYear W23164526152020 @default.
• W2316452615 countsByYear W23164526152022 @default.
• W2316452615 countsByYear W23164526152023 @default.
• W2316452615 crossrefType "journal-article" @default.
• W2316452615 hasAuthorship W2316452615A5000633937 @default.
• W2316452615 hasAuthorship W2316452615A5008549101 @default.
• W2316452615 hasAuthorship W2316452615A5021126434 @default.
• W2316452615 hasAuthorship W2316452615A5032413419 @default.
• W2316452615 hasAuthorship W2316452615A5039463412 @default.
• W2316452615 hasAuthorship W2316452615A5057180752 @default.
• W2316452615 hasAuthorship W2316452615A5057379050 @default.
• W2316452615 hasAuthorship W2316452615A5058589470 @default.
• W2316452615 hasAuthorship W2316452615A5059096605 @default.
• W2316452615 hasAuthorship W2316452615A5067197714 @default.
• W2316452615 hasAuthorship W2316452615A5067876698 @default.
• W2316452615 hasAuthorship W2316452615A5077738482 @default.
• W2316452615 hasAuthorship W2316452615A5088151988 @default.
• W2316452615 hasBestOaLocation W23164526151 @default.
• W2316452615 hasConcept C120665830 @default.
• W2316452615 hasConcept C121332964 @default.
• W2316452615 hasConcept C12554922 @default.
• W2316452615 hasConcept C146088050 @default.
• W2316452615 hasConcept C155672457 @default.
• W2316452615 hasConcept C171250308 @default.
• W2316452615 hasConcept C175369904 @default.
• W2316452615 hasConcept C185592680 @default.
• W2316452615 hasConcept C192562407 @default.
• W2316452615 hasConcept C202751555 @default.
• W2316452615 hasConcept C2777339698 @default.
• W2316452615 hasConcept C2778889443 @default.
• W2316452615 hasConcept C46141821 @default.
• W2316452615 hasConcept C54355233 @default.
• W2316452615 hasConcept C55493867 @default.
• W2316452615 hasConcept C81885089 @default.
• W2316452615 hasConcept C86803240 @default.
• W2316452615 hasConcept C87023908 @default.
• W2316452615 hasConcept C93877712 @default.
• W2316452615 hasConceptScore W2316452615C120665830 @default.
• W2316452615 hasConceptScore W2316452615C121332964 @default.
• W2316452615 hasConceptScore W2316452615C12554922 @default.
• W2316452615 hasConceptScore W2316452615C146088050 @default.
• W2316452615 hasConceptScore W2316452615C155672457 @default.
• W2316452615 hasConceptScore W2316452615C171250308 @default.

• next