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• W2316463223 abstract "Event Abstract Back to Event Tangential and radial epileptic spike activity: different sensitivity in EEG and MEG Jens Haueisen1*, Michael Funke2, Daniel Güllmar3 and Roland Eichardt3 1 Technical University Ilmenau, Germany 2 University of Utah, United States 3 University Hospital Jena, Germany Observations in epileptic patients show that interictal spikes are sometimes only visible in EEG and sometimes only visible in MEG. This observation cannot readily be explained by the theoretical sensitivities of EEG and MEG based on analytical models. Hence we aimed to study the influence of radial and tangential spike and background activity in realistic numerical head models. We analyze the signal-to-noise ratio (SNR) of simulated spikes at varying orientations and with varying background activity in twelve brain regions for four volunteers. Different levels of background activity are modeled by adjusting the amplitudes of several thousand dipoles distributed in the cortex. For a fixed realistic background activity, we find a higher SNR for spikes in the MEG as long as the spike orientation is not more than 30 degrees deviating from the tangential direction. Vice versa, the SNR for spikes in the EEG is higher as long as the spike orientation is not more than 45 degrees deviating from the radial direction. When the radial background activity is selectively increased, the sensitivity of EEG for radially oriented spikes is decreased, and when the tangential background activity is selectively increased, the sensitivity of MEG for tangentially oriented spikes is decreased. Our simulations provide a possible explanation for the clinically observed differences in epileptic spike detection in EEG and MEG. Combined EEG / MEG data analysis will improve epileptic spike detection. Conference: Biomag 2010 - 17th International Conference on Biomagnetism , Dubrovnik, Croatia, 28 Mar - 1 Apr, 2010. Presentation Type: Poster Presentation Topic: Epilepsy Citation: Haueisen J, Funke M, Güllmar D and Eichardt R (2010). Tangential and radial epileptic spike activity: different sensitivity in EEG and MEG. Front. Neurosci. Conference Abstract: Biomag 2010 - 17th International Conference on Biomagnetism . doi: 10.3389/conf.fnins.2010.06.00322 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 06 Apr 2010; Published Online: 06 Apr 2010. * Correspondence: Jens Haueisen, Technical University Ilmenau, Ilmenau, Germany, jens.haueisen@tu-ilmenau.de Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Jens Haueisen Michael Funke Daniel Güllmar Roland Eichardt Google Jens Haueisen Michael Funke Daniel Güllmar Roland Eichardt Google Scholar Jens Haueisen Michael Funke Daniel Güllmar Roland Eichardt PubMed Jens Haueisen Michael Funke Daniel Güllmar Roland Eichardt Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2316463223 date "2010-01-01" @default.
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• W2316463223 title "Tangential and radial epileptic spike activity: different sensitivity in EEG and MEG" @default.
• W2316463223 doi "https://doi.org/10.3389/conf.fnins.2010.06.00322" @default.
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