Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316502309> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2316502309 abstract "Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DCBackground: Higher adiposity during childhood has been reported to be associated with reduced breast cancer risk. We hypothesize that adiposity may play a role in later breast cancer development through its influence on the insulin pathway.Objectives: To prospectively examine associations between baseline childhood adiposity and longitudinal measures of serum insulin related biomarkers (IRBS) (insulin, C-peptide, glucose, homeostasis model assessment of insulin resistance [HOMA]) among girls in the DISC.Methods: The present study includes 270 of the 301 girls who participated in the DISC (median follow-up: 7 yrs). Among these girls, 224 girls had premenarcheal fasting blood samples and 203 girls had postmenarcheal fasting blood samples collected on at least one of four visits: baseline, years 3, 5 and last visit. Weight, height and waist circumference (WC) were measured at multiple visits. General and central adiposity were assessed as body mass index (BMI)-for-age percentile (BMIPCT) and WC, respectively. Adjusted geometric means of IRBS were calculated within quintiles of baseline BMIPCT and WC. Baseline BMIPCT and WC were also modeled as continuous variables to estimate their associations with longitudinal measures of IRBS, using multivariable linear mixed-effect models. All adjusted analyses included age, age2, treatment group, baseline height, and physical activity.Results: Premenarcheal girls in the lowest quintile of baseline BMIPCT had the lowest geometric mean of all four IRBS. Both pre- and post-menarcheal girls in the lowest quintile of baseline WC had the lowest geometric mean of insulin, C-peptide and HOMA. Results from continuous analyses of the associations between baseline BMIPCT/WC and IRBS are shown in [Table 1][1].Conclusion: Results show higher BMIPCT in girls at baseline is associated with higher levels of IRBS premenarche, while higher WC is associated with higher IRBS both pre- and postmenarche.View this table:Table 1. Percent change in concentrations of IRBS based on baseline BMIPCT and WC in adolescent girlCitation Format: Zhenzhen Zhang, Jean M. Kerver, Joseph C. Gardiner, Joanne F. Dorgan, Ellen M. Velie. Anthropometric factors and insulin related biomarkers in adolescent girls: Results from the Dietary Intervention Study in Children (DISC). [abstract]. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 2523. doi:10.1158/1538-7445.AM2013-2523Note: This abstract was not presented at the AACR Annual Meeting 2013 because the presenter was unable to attend. [1]: #T1" @default.
- W2316502309 created "2016-06-24" @default.
- W2316502309 creator A5002817767 @default.
- W2316502309 creator A5030319979 @default.
- W2316502309 creator A5065260102 @default.
- W2316502309 creator A5066361215 @default.
- W2316502309 creator A5080707093 @default.
- W2316502309 date "2013-04-15" @default.
- W2316502309 modified "2023-09-27" @default.
- W2316502309 title "Abstract 2523: Anthropometric factors and insulin related biomarkers in adolescent girls: Results from the Dietary Intervention Study in Children (DISC)." @default.
- W2316502309 doi "https://doi.org/10.1158/1538-7445.am2013-2523" @default.
- W2316502309 hasPublicationYear "2013" @default.
- W2316502309 type Work @default.
- W2316502309 sameAs 2316502309 @default.
- W2316502309 citedByCount "0" @default.
- W2316502309 crossrefType "proceedings-article" @default.
- W2316502309 hasAuthorship W2316502309A5002817767 @default.
- W2316502309 hasAuthorship W2316502309A5030319979 @default.
- W2316502309 hasAuthorship W2316502309A5065260102 @default.
- W2316502309 hasAuthorship W2316502309A5066361215 @default.
- W2316502309 hasAuthorship W2316502309A5080707093 @default.
- W2316502309 hasConcept C105795698 @default.
- W2316502309 hasConcept C122048520 @default.
- W2316502309 hasConcept C126322002 @default.
- W2316502309 hasConcept C134018914 @default.
- W2316502309 hasConcept C144024400 @default.
- W2316502309 hasConcept C149923435 @default.
- W2316502309 hasConcept C2776193436 @default.
- W2316502309 hasConcept C2777391703 @default.
- W2316502309 hasConcept C2779306644 @default.
- W2316502309 hasConcept C2779422640 @default.
- W2316502309 hasConcept C2780221984 @default.
- W2316502309 hasConcept C2780586474 @default.
- W2316502309 hasConcept C33923547 @default.
- W2316502309 hasConcept C61427482 @default.
- W2316502309 hasConcept C71924100 @default.
- W2316502309 hasConceptScore W2316502309C105795698 @default.
- W2316502309 hasConceptScore W2316502309C122048520 @default.
- W2316502309 hasConceptScore W2316502309C126322002 @default.
- W2316502309 hasConceptScore W2316502309C134018914 @default.
- W2316502309 hasConceptScore W2316502309C144024400 @default.
- W2316502309 hasConceptScore W2316502309C149923435 @default.
- W2316502309 hasConceptScore W2316502309C2776193436 @default.
- W2316502309 hasConceptScore W2316502309C2777391703 @default.
- W2316502309 hasConceptScore W2316502309C2779306644 @default.
- W2316502309 hasConceptScore W2316502309C2779422640 @default.
- W2316502309 hasConceptScore W2316502309C2780221984 @default.
- W2316502309 hasConceptScore W2316502309C2780586474 @default.
- W2316502309 hasConceptScore W2316502309C33923547 @default.
- W2316502309 hasConceptScore W2316502309C61427482 @default.
- W2316502309 hasConceptScore W2316502309C71924100 @default.
- W2316502309 hasLocation W23165023091 @default.
- W2316502309 hasOpenAccess W2316502309 @default.
- W2316502309 hasPrimaryLocation W23165023091 @default.
- W2316502309 hasRelatedWork W164414459 @default.
- W2316502309 hasRelatedWork W1974637031 @default.
- W2316502309 hasRelatedWork W1978413383 @default.
- W2316502309 hasRelatedWork W2035195537 @default.
- W2316502309 hasRelatedWork W2056297012 @default.
- W2316502309 hasRelatedWork W2082559037 @default.
- W2316502309 hasRelatedWork W2115222364 @default.
- W2316502309 hasRelatedWork W2147757513 @default.
- W2316502309 hasRelatedWork W2149933601 @default.
- W2316502309 hasRelatedWork W2160140739 @default.
- W2316502309 hasRelatedWork W2164617952 @default.
- W2316502309 hasRelatedWork W2326717963 @default.
- W2316502309 hasRelatedWork W2473409373 @default.
- W2316502309 hasRelatedWork W2741127593 @default.
- W2316502309 hasRelatedWork W2781777062 @default.
- W2316502309 hasRelatedWork W2810592055 @default.
- W2316502309 hasRelatedWork W2911772904 @default.
- W2316502309 hasRelatedWork W2912424263 @default.
- W2316502309 hasRelatedWork W2920224498 @default.
- W2316502309 hasRelatedWork W2965509597 @default.
- W2316502309 isParatext "false" @default.
- W2316502309 isRetracted "false" @default.
- W2316502309 magId "2316502309" @default.
- W2316502309 workType "article" @default.