FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316572351> ?p ?o ?g. }

• W2316572351 endingPage "771" @default.
• W2316572351 startingPage "771" @default.
• W2316572351 abstract "This study evaluated the effects of the human serine protease inhibitor alpha-1-antitrypsin (AAT) on in vitro excystation and infectivity of Cryptosporidium parvum. Excystation was monitored at 37 C in RPMI medium in the presence of 0, 100, 500, or 1,000 micrograms/ml AAT. AAT significantly inhibited (P < 0.05) excystation of bleach-decontaminated oocysts in a concentration-dependent manner at incubation intervals from 15 to 90 min but did not alter the excystation dynamics of unbleached oocysts. Bleach-treated oocysts, suspended in RPMI containing 0, 1, 10, 100, 500, or 1,000 micrograms/ml AAT, were used to inoculate bovine fallopian tube epithelial (BFTE) cell monolayers. Alternately, sporozoites, excysted at 37 degrees C and collected by filtration, were used to inoculate BFTE cells under the same conditions. The mean number of parasites counted in AAT-treated, oocyst-inoculated cells was significantly less (P < 0.01) than control mean values at 24 and 48 hr post-inoculation (PI); longer PI intervals (72-96 hr) exhibited a decreased inhibitory effect. AAT did not inhibit parasite infection when cultures were inoculated with C. parvum sporozoites. The findings of this study show that the anticryptosporidial potential of AAT is primarily associated with an antagonistic effect on oocyst excystation." @default.
• W2316572351 created "2016-06-24" @default.
• W2316572351 creator A5032695622 @default.
• W2316572351 creator A5035862075 @default.
• W2316572351 creator A5088139118 @default.
• W2316572351 date "1997-08-01" @default.
• W2316572351 modified "2023-10-18" @default.
• W2316572351 title "Antagonistic Effect of Human Alpha-1-Antitrypsin on Excystation of Cryptosporidium parvum Oocysts" @default.
• W2316572351 cites W1971001936 @default.
• W2316572351 cites W1978039635 @default.
• W2316572351 cites W1979239944 @default.
• W2316572351 cites W1981754939 @default.
• W2316572351 cites W1996162070 @default.
• W2316572351 cites W1998603390 @default.
• W2316572351 cites W1998906916 @default.
• W2316572351 cites W2003583980 @default.
• W2316572351 cites W2019402469 @default.
• W2316572351 cites W2036073074 @default.
• W2316572351 cites W2038120139 @default.
• W2316572351 cites W2057320510 @default.
• W2316572351 cites W2068360894 @default.
• W2316572351 cites W2083799571 @default.
• W2316572351 cites W2087017424 @default.
• W2316572351 cites W2144475103 @default.
• W2316572351 cites W2169251827 @default.
• W2316572351 cites W2176557328 @default.
• W2316572351 cites W2312615102 @default.
• W2316572351 cites W2318580069 @default.
• W2316572351 cites W2330618735 @default.
• W2316572351 cites W2412716015 @default.
• W2316572351 cites W2415499904 @default.
• W2316572351 cites W284542904 @default.
• W2316572351 doi "https://doi.org/10.2307/3284264" @default.
• W2316572351 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9267429" @default.
• W2316572351 hasPublicationYear "1997" @default.
• W2316572351 type Work @default.
• W2316572351 sameAs 2316572351 @default.
• W2316572351 citedByCount "18" @default.
• W2316572351 countsByYear W23165723512012 @default.
• W2316572351 countsByYear W23165723512014 @default.
• W2316572351 countsByYear W23165723512017 @default.
• W2316572351 countsByYear W23165723512022 @default.
• W2316572351 countsByYear W23165723512023 @default.
• W2316572351 crossrefType "journal-article" @default.
• W2316572351 hasAuthorship W2316572351A5032695622 @default.
• W2316572351 hasAuthorship W2316572351A5035862075 @default.
• W2316572351 hasAuthorship W2316572351A5088139118 @default.
• W2316572351 hasConcept C106358424 @default.
• W2316572351 hasConcept C136764020 @default.
• W2316572351 hasConcept C159047783 @default.
• W2316572351 hasConcept C180032290 @default.
• W2316572351 hasConcept C181199279 @default.
• W2316572351 hasConcept C202751555 @default.
• W2316572351 hasConcept C203014093 @default.
• W2316572351 hasConcept C2522874641 @default.
• W2316572351 hasConcept C25642318 @default.
• W2316572351 hasConcept C2776714187 @default.
• W2316572351 hasConcept C2777795018 @default.
• W2316572351 hasConcept C2777807008 @default.
• W2316572351 hasConcept C2778566189 @default.
• W2316572351 hasConcept C41008148 @default.
• W2316572351 hasConcept C55493867 @default.
• W2316572351 hasConcept C71928629 @default.
• W2316572351 hasConcept C86803240 @default.
• W2316572351 hasConcept C89423630 @default.
• W2316572351 hasConceptScore W2316572351C106358424 @default.
• W2316572351 hasConceptScore W2316572351C136764020 @default.
• W2316572351 hasConceptScore W2316572351C159047783 @default.
• W2316572351 hasConceptScore W2316572351C180032290 @default.
• W2316572351 hasConceptScore W2316572351C181199279 @default.
• W2316572351 hasConceptScore W2316572351C202751555 @default.
• W2316572351 hasConceptScore W2316572351C203014093 @default.
• W2316572351 hasConceptScore W2316572351C2522874641 @default.
• W2316572351 hasConceptScore W2316572351C25642318 @default.
• W2316572351 hasConceptScore W2316572351C2776714187 @default.
• W2316572351 hasConceptScore W2316572351C2777795018 @default.
• W2316572351 hasConceptScore W2316572351C2777807008 @default.
• W2316572351 hasConceptScore W2316572351C2778566189 @default.
• W2316572351 hasConceptScore W2316572351C41008148 @default.
• W2316572351 hasConceptScore W2316572351C55493867 @default.
• W2316572351 hasConceptScore W2316572351C71928629 @default.
• W2316572351 hasConceptScore W2316572351C86803240 @default.
• W2316572351 hasConceptScore W2316572351C89423630 @default.
• W2316572351 hasIssue "4" @default.
• W2316572351 hasLocation W23165723511 @default.
• W2316572351 hasLocation W23165723512 @default.
• W2316572351 hasOpenAccess W2316572351 @default.
• W2316572351 hasPrimaryLocation W23165723511 @default.
• W2316572351 hasRelatedWork W1970557517 @default.
• W2316572351 hasRelatedWork W1992407739 @default.
• W2316572351 hasRelatedWork W1996067496 @default.
• W2316572351 hasRelatedWork W2017565148 @default.
• W2316572351 hasRelatedWork W2032566646 @default.
• W2316572351 hasRelatedWork W2135835583 @default.
• W2316572351 hasRelatedWork W2316572351 @default.
• W2316572351 hasRelatedWork W2317012277 @default.
• W2316572351 hasRelatedWork W2438802912 @default.
• W2316572351 hasRelatedWork W2768616041 @default.

• next