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• W2316597323 abstract "The ability of salivary secretions and sputum sol from patients with chronic bronchitis to inhibit the adhesion of non-serotypable Haemophilus influenzae to human buccal epithelial cells has been examined. Specific H. influenzae antibodies were measured by an enzyme-linked immunosorbent assay (ELISA). Saliva and sputum levels of anti- H. influenzae immunoglobulin A (IgA) antibody were related inversely to buccal cell adherence (r = - 0·92). Absorption of saliva and sputum sol with H. influenzae removed antibody detected by ELISA but only partially removed inhibition of attachment of bacteria. In patients with a history of recurrent bronchitis significantly more inhibitory activity remained after absorption of the secretory IgA (sIgA) specific antibody compared with patients who were resistant to acute episodes of infection (P <0·05). These observations suggest that factors, other than sIgA. are present in respiratory secretions and are capable of modulating H. influenzae attachment to buccal epithelial cells." @default.
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• W2316597323 date "1990-10-01" @default.
• W2316597323 modified "2023-09-23" @default.
• W2316597323 title "Inhibition of adhesion ofHaemophilus influenzaeto buccal cells by respiratory secretions" @default.
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• W2316597323 doi "https://doi.org/10.1038/icb.1990.45" @default.
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