Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316638959> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2316638959 endingPage "1109" @default.
- W2316638959 startingPage "1109" @default.
- W2316638959 abstract "Cardiac arrhythmia occurs frequently worldwide, and in severe cases can be fatal. Mitochondria are the power plants of cardiomyocytes. In recent studies, mitochondria under certain stimuli produced excessive reactive oxygen species (ROS), which affect the normal function of cardiomyocytes through ion channels and related proteins. Mitochondrial oxidative stress (MOS) plays a key role in diseases with multifactorial etiopathogenesis, such as arrhythmia; MOS can lead to arrhythmias such as atrial fibrillation and ventricular tachycardia. This review discusses the mechanisms of arrhythmias caused by MOS, particularly of ROS produced by mitochondria. MOS can cause arrhythmias by affecting the activities of Ca2+-related proteins, the mitochondrial permeability transition pore protein, connexin 43, hyperpolarization-activated cyclic nucleotide-gated potassium channel 4, and ion channels. Based on these mechanisms, we discuss possible new treatments for arrhythmia. Targeted treatments focusing on mitochondria may reduce the progression of arrhythmias, as well as the occurrence of severe arrhythmias, and may be effective for personalized disease prevention." @default.
- W2316638959 created "2016-06-24" @default.
- W2316638959 creator A5081800288 @default.
- W2316638959 date "1989-09-01" @default.
- W2316638959 modified "2023-09-26" @default.
- W2316638959 title "Bioactive molecules: Anthracyline and anthracenedione-based anticancer agents" @default.
- W2316638959 doi "https://doi.org/10.1016/0300-9084(89)90121-1" @default.
- W2316638959 hasPublicationYear "1989" @default.
- W2316638959 type Work @default.
- W2316638959 sameAs 2316638959 @default.
- W2316638959 citedByCount "0" @default.
- W2316638959 crossrefType "journal-article" @default.
- W2316638959 hasAuthorship W2316638959A5081800288 @default.
- W2316638959 hasConcept C126322002 @default.
- W2316638959 hasConcept C13591479 @default.
- W2316638959 hasConcept C158157758 @default.
- W2316638959 hasConcept C170493617 @default.
- W2316638959 hasConcept C185592680 @default.
- W2316638959 hasConcept C190283241 @default.
- W2316638959 hasConcept C2776151105 @default.
- W2316638959 hasConcept C2779161974 @default.
- W2316638959 hasConcept C2780228694 @default.
- W2316638959 hasConcept C28859421 @default.
- W2316638959 hasConcept C2988455589 @default.
- W2316638959 hasConcept C31573885 @default.
- W2316638959 hasConcept C48349386 @default.
- W2316638959 hasConcept C50254741 @default.
- W2316638959 hasConcept C55493867 @default.
- W2316638959 hasConcept C60644358 @default.
- W2316638959 hasConcept C71924100 @default.
- W2316638959 hasConcept C79879829 @default.
- W2316638959 hasConcept C83743174 @default.
- W2316638959 hasConcept C86803240 @default.
- W2316638959 hasConcept C95444343 @default.
- W2316638959 hasConcept C98274493 @default.
- W2316638959 hasConceptScore W2316638959C126322002 @default.
- W2316638959 hasConceptScore W2316638959C13591479 @default.
- W2316638959 hasConceptScore W2316638959C158157758 @default.
- W2316638959 hasConceptScore W2316638959C170493617 @default.
- W2316638959 hasConceptScore W2316638959C185592680 @default.
- W2316638959 hasConceptScore W2316638959C190283241 @default.
- W2316638959 hasConceptScore W2316638959C2776151105 @default.
- W2316638959 hasConceptScore W2316638959C2779161974 @default.
- W2316638959 hasConceptScore W2316638959C2780228694 @default.
- W2316638959 hasConceptScore W2316638959C28859421 @default.
- W2316638959 hasConceptScore W2316638959C2988455589 @default.
- W2316638959 hasConceptScore W2316638959C31573885 @default.
- W2316638959 hasConceptScore W2316638959C48349386 @default.
- W2316638959 hasConceptScore W2316638959C50254741 @default.
- W2316638959 hasConceptScore W2316638959C55493867 @default.
- W2316638959 hasConceptScore W2316638959C60644358 @default.
- W2316638959 hasConceptScore W2316638959C71924100 @default.
- W2316638959 hasConceptScore W2316638959C79879829 @default.
- W2316638959 hasConceptScore W2316638959C83743174 @default.
- W2316638959 hasConceptScore W2316638959C86803240 @default.
- W2316638959 hasConceptScore W2316638959C95444343 @default.
- W2316638959 hasConceptScore W2316638959C98274493 @default.
- W2316638959 hasIssue "9-10" @default.
- W2316638959 hasLocation W23166389591 @default.
- W2316638959 hasOpenAccess W2316638959 @default.
- W2316638959 hasPrimaryLocation W23166389591 @default.
- W2316638959 hasRelatedWork W1984090039 @default.
- W2316638959 hasRelatedWork W2018093151 @default.
- W2316638959 hasRelatedWork W2021693564 @default.
- W2316638959 hasRelatedWork W2046857128 @default.
- W2316638959 hasRelatedWork W2087442345 @default.
- W2316638959 hasRelatedWork W2108998280 @default.
- W2316638959 hasRelatedWork W2468879160 @default.
- W2316638959 hasRelatedWork W3120339133 @default.
- W2316638959 hasRelatedWork W3194998566 @default.
- W2316638959 hasRelatedWork W4200074111 @default.
- W2316638959 hasVolume "71" @default.
- W2316638959 isParatext "false" @default.
- W2316638959 isRetracted "false" @default.
- W2316638959 magId "2316638959" @default.
- W2316638959 workType "article" @default.