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- W2316682019 abstract "Ghrelin is a 28-amino-acid peptide hormone that is secreted primarily by stomach cells with lesser amounts secreted by other cells (including the hypothalamus). Some evidence suggests that increases in estrogen enhance the synthesis or acylation of ghrelin. PURPOSE: The present study was designed to examine the effects of 8 weeks aerobic training of different exercise durations and corresponding exercise volumes on resting plasma ghrelin levels in rats. METHODS: Fifty adult Wistar male rats (6-8 weeks old, 270±10g) were randomly divided into five groups: 30, 60 and 90 min training, sham and control groups. All experimental groups performed an 8-week treadmill running program at the same velocity and 0 gradient for 30, 60 or 90 min/day, 5 days/week. The concentration of ghrelin in blood samples was assessed after 8 weeks and 72 hours following the final training session. The ghrelin concentration was measured by ELISA Possible statistically significant differences between groups after the exercise training intervention was determined by one-way ANOVA, and LSD test was used for a post-hoc analysis. RESULTS: Resting concentrations of ghrelin were unchanged after training. Similarly, there were no observed change in insulin and glucose concentrations compared with the control group. CONCLUSIONS: However there was a significant difference in estrogen concentrations when compared with the control group. The data suggest that although exercise training duration/volume augmented blood concentrations of circulating estradiol in male rats, there was no effect on ghrelin." @default.
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- W2316682019 date "2011-05-01" @default.
- W2316682019 modified "2023-10-14" @default.
- W2316682019 title "The Effect Of Eight Weeks Of Endurance Training Of Different Durations On Ghrelin, Insulin, Glucose And Estrogen In Male Rats" @default.
- W2316682019 doi "https://doi.org/10.1249/01.mss.0000401856.09472.0b" @default.
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