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• W2316731008 abstract "Technical advances have permitted the combination of EUS with fine needleaspiration biopsy (EUS-FNAB) permitting both morphological and histo-/cytological analyses in GI tumours. The complication rate following EUS-FNAB remains poorly defined and patients are usually hospitalised following the procedure for observation surveillance. Aim: To evaluate the immediate complications in patients undergoing EUS-FNAB and define whether overnight in-hospital surveillance was justified. Methods: Between Jan.1998 & Oct.1999, the case records of 222 consecutive patients undergoing EUS-FNAB for lesions of the upper or lower digestive tract were retrospectively examined. The population included 120 males, mean age of 58 yr.(19-84). All procedures were performed under general anaesthesia. Complications (including local complications resulting from endoscopy/biopsy or clinical complications following the procedure) were defined from induction of anaesthesia until 24 hr. after the procedure. Potential risk factors for the development of complications were also analysed including: site and nature of the lesion, presence of portal hypertension, and number of biopsy passes. Results: EUS-FNAB involved the pancreas in 177 cases (head 113, body 46, tail 18). Pancreatic tumours type included: solid (73), cystic (88) and mixed (16). The nature and location of other lesions were: lymph nodes 27 (mediastinal 13, coeliac 8, porta hepatis 6); peri-rectal 5; oesophageal 5; gastric 3; duodenal 2; ovarian 2; adrenal gland 1. The mean number of biopys/patient was 2.16 (1-10). Complications were observed in 14 patients (6.3%). Those occurring during EUS-FNAB totalled 11 (intra-tumour haemorrhage in 6 and small haematomas of the gastrointestinal wall in 5), none of which resulted in clinical compromise and all were discharged the following day. Complications were significant in 3 patients (1.4%): acute pancreatitis in one patient (Balthazar B) which resolved within 24 hr.; inhalation pneumonia in two, both of whom were treated successfully with antibiotics. No complications were observed in the 16 patients (7.2%) with portal hypertension. Neither the site nor the nature of the lesion was predictive of the development of complications. Conclusion: The risk of complications from EUS-FNAB does not appear superior to that from standard EUS alone and this procedure may be recommended in an ambulatory fashion, reserving over-night surveillance for those with peri-procedure complications." @default.
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• W2316731008 date "2000-04-01" @default.
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• W2316731008 title "7016 Endoscopic ultrasound fine-needle aspiration biopsy (eus-fnab): can the procedure be performed safely as out-patients?" @default.
• W2316731008 doi "https://doi.org/10.1016/s0016-5107(00)14687-5" @default.
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