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- W2316805784 abstract "Objective: To evaluate behavioral variant frontotemporal dementia (bvFTD) patients9 abilities to coordinate language with a communicative partner. Background bvFTD is characterized by executive limitations and a disorder of behavioral/social comportment but with relatively spared language. Effective communication requires a speaker and a conversational partner to “coordinate” in order to optimize communicative clarity. Coordination involves adjusting speech and comprehension to accommodate a partner9s perspective. Previous work has demonstrated coordination limitations in bvFTD, but it is unknown whether coordination limitations impact communication. Design/Methods: 7 bvFTD patients and 12 healthy seniors (HS) were presented with a two-scene story in which a target animal moved from one position to another in each scene. “Competitors” were included in each scene and were the same animal type (e.g., pig) but differed by one of three types of visual features (color, size, pattern). Therefore, participants were required to use appropriate adjectives to describe the target animal. Participants were instructed to describe the scene with sufficient clarity so a communicative partner could understand which animal was moving. Each story contained either zero (“pig”), one (“red pig”) or three (“large, red, spotted pig”) competitors. Participants9 responses were transcribed and we coded for accuracy producing the correct adjective(s). We used voxel-based morphometry (VBM) to relate coordination limitations to gray matter (GM) atrophy in bvFTD. Results: We observed a Group by Competitors interaction for accuracy [F=12.4; p Conclusions: bvFTD have limitations coordinating with a conversational partner and this may be due in part to executive limitations associated with caudate atrophy. Supported by: HD060406,NS44266,NS53488,AG15116,AG17586,AG32953,The Wyncote Foundation. Disclosure: Dr. McMillan has nothing to disclose. Dr. Rascovsky has nothing to disclose. Dr. Khella has nothing to disclose. Dr. Clark has nothing to disclose. Dr. Grossman has nothing to disclose." @default.
- W2316805784 created "2016-06-24" @default.
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- W2316805784 date "2012-04-22" @default.
- W2316805784 modified "2023-10-16" @default.
- W2316805784 title "Coordination Limitations in Behavioral Variant Frontotemporal Dementia Have Consequences for Communication (P07.174)" @default.
- W2316805784 doi "https://doi.org/10.1212/wnl.78.1_meetingabstracts.p07.174" @default.
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