Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316844042> ?p ?o ?g. }
- W2316844042 abstract "Since its derivation, much has been learned about the proinflammatory inducing cytokine interleukin-18, and its role in resolving infectious diseases. Studies to date that examined interleukin-18 have shown that endogenously induced interleukin-18 plays an important protective role in some viral and bacterial infections. However, interleukin-18 has a limited role in protective immunity to Salmonella infections, and is secondary to the protective role of interleukin-12. This lack of sensitivity to interleukin-18 may be in part related to the dependence on interleukin-12 for interleukin-18 receptor expression and to the nanomolar concentrations that are required. Nonetheless, an understanding of how some pathogens have evolved to circumvent interleukin-18 and of how interleukin-18 can be effectively induced are essential to our ability to develop better vaccines against enteric pathogens." @default.
- W2316844042 created "2016-06-24" @default.
- W2316844042 creator A5057356831 @default.
- W2316844042 date "2001-06-01" @default.
- W2316844042 modified "2023-09-26" @default.
- W2316844042 title "The protective role of interleukin-18 in Salmonella infection" @default.
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- W2316844042 doi "https://doi.org/10.1097/00001432-200106000-00004" @default.
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