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- W2316930079 abstract "To assess the efficacy of modafinil for the treatment of new learning and memory deficits and fatigue in multiple sclerosis. Only 1 previous study in the literature, to our knowledge, examined the effect of modafinil on cognition specifically in persons with multiple sclerosis.Sixteen patients with a diagnosis of multiple sclerosis (MS) and documented new learning impairment completed the study. In a 5-week randomized, double-blinded, crossover design, participants received either a single daily oral dose of modafinil (200 mg) or placebo for 2 weeks. A 1-week washout period was included between study arms.No effect of modafinil was noted on learning and memory performance. Participants taking 200 mg of modafinil showed improvement in 1 of the 2 working memory measures administered, the Wechsler Adult Intelligence Scale-III (WAIS-III) Letter-Number Sequencing task, as compared with those on placebo. Treatment with modafinil did not have a beneficial effect in reducing self-reported fatigue. No changes were noted on the Modified Fatigue Impact Scale or the Fatigue Severity Scale with the treatment of modafinil, as compared with placebo.Findings indicate that 200 mg of modafinil has the potential to improve working memory in persons with MS. These findings suggest that modafinil may enhance aspects of cognition in persons with MS and may be an effective adjunct to clinical rehabilitation interventions." @default.
- W2316930079 created "2016-06-24" @default.
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- W2316930079 date "2016-02-01" @default.
- W2316930079 modified "2023-10-10" @default.
- W2316930079 title "Cognitive effects of modafinil in patients with multiple sclerosis: A clinical trial." @default.
- W2316930079 cites W155259919 @default.
- W2316930079 cites W1607171655 @default.
- W2316930079 cites W1830481607 @default.
- W2316930079 cites W1914703486 @default.
- W2316930079 cites W1966415679 @default.
- W2316930079 cites W1967809452 @default.
- W2316930079 cites W1968251262 @default.
- W2316930079 cites W1968852226 @default.
- W2316930079 cites W1971635815 @default.
- W2316930079 cites W1975163395 @default.
- W2316930079 cites W1975930259 @default.
- W2316930079 cites W1978392406 @default.
- W2316930079 cites W1983187546 @default.
- W2316930079 cites W1985050648 @default.
- W2316930079 cites W1986645717 @default.
- W2316930079 cites W1991497633 @default.
- W2316930079 cites W1992999272 @default.
- W2316930079 cites W1994718306 @default.
- W2316930079 cites W1995597901 @default.
- W2316930079 cites W1995692784 @default.
- W2316930079 cites W1997146742 @default.
- W2316930079 cites W1998609863 @default.
- W2316930079 cites W2008348302 @default.
- W2316930079 cites W2019570771 @default.
- W2316930079 cites W2020212968 @default.
- W2316930079 cites W2021799277 @default.
- W2316930079 cites W2026775116 @default.
- W2316930079 cites W2027072836 @default.
- W2316930079 cites W2034683974 @default.
- W2316930079 cites W2037902784 @default.
- W2316930079 cites W2040345079 @default.
- W2316930079 cites W2044533734 @default.
- W2316930079 cites W2045643058 @default.
- W2316930079 cites W2046130760 @default.
- W2316930079 cites W2047226578 @default.
- W2316930079 cites W2056736742 @default.
- W2316930079 cites W2062453566 @default.
- W2316930079 cites W2062761396 @default.
- W2316930079 cites W2066115280 @default.
- W2316930079 cites W2070593108 @default.
- W2316930079 cites W2073297721 @default.
- W2316930079 cites W2073330852 @default.
- W2316930079 cites W2076585890 @default.
- W2316930079 cites W2078184061 @default.
- W2316930079 cites W2079072219 @default.
- W2316930079 cites W2091596722 @default.
- W2316930079 cites W2093576807 @default.
- W2316930079 cites W2093959215 @default.
- W2316930079 cites W2107879282 @default.
- W2316930079 cites W2108230902 @default.
- W2316930079 cites W2109159740 @default.
- W2316930079 cites W2109763774 @default.
- W2316930079 cites W2110742832 @default.
- W2316930079 cites W2114242035 @default.
- W2316930079 cites W2122011624 @default.
- W2316930079 cites W2123200781 @default.
- W2316930079 cites W2130632081 @default.
- W2316930079 cites W2133071347 @default.
- W2316930079 cites W2133468657 @default.
- W2316930079 cites W2152215092 @default.
- W2316930079 cites W2154332982 @default.
- W2316930079 cites W2161822858 @default.
- W2316930079 cites W2162141299 @default.
- W2316930079 cites W2163394083 @default.
- W2316930079 cites W2165031188 @default.
- W2316930079 cites W2167819459 @default.
- W2316930079 cites W2170462162 @default.
- W2316930079 cites W2287117136 @default.
- W2316930079 cites W2406354566 @default.
- W2316930079 cites W2558196388 @default.
- W2316930079 cites W2912009534 @default.
- W2316930079 cites W66447799 @default.
- W2316930079 doi "https://doi.org/10.1037/a0039919" @default.
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- W2316930079 hasPublicationYear "2016" @default.
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