FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316971979> ?p ?o ?g. }

• W2316971979 endingPage "476" @default.
• W2316971979 startingPage "469" @default.
• W2316971979 abstract "Increased levels of pro-inflammatory factors, markers of oxidative stress and insulin resistance during pregnancy have been associated with the development of pre-eclampsia. There is some evidence to suggest that calcium supplement and aspirin can reduce the risk of the disorder. To our knowledge, no reports are available indicating the effects of consumed calcium supplement plus aspirin on high sensitivity C-reactive protein (hs-CRP), oxidative stress parameters and insulin resistance in pregnant women at risk for pre-eclampsia. This study was designed to investigate the effects of consumed calcium supplement plus low-dose aspirin on hs-CRP, oxidative stress parameters and insulin resistance among Iranian pregnant women at risk for pre-eclampsia. This randomized single-blind controlled clinical trial was carried out among 42 pregnant women at risk for pre-eclampsia, primigravida, aged 18-40 year old who were carrying singleton pregnancy at their third trimester. Subjects were randomly assigned to received either the placebo (n = 22) or calcium supplement plus low-dose aspirin (n = 20) for 9 weeks. Calcium supplement plus low-dose aspirin were containing 500 mg carbonate calcium plus 80 mg aspirin. Fasting blood samples were taken at baseline and after 9 weeks intervention to measure serum hs-CRP, oxidative stress parameters including plasma Total Antioxidant Capacity (TAC) and Total Glutathione (GSH), Fasting Plasma Glucose (FPG), serum insulin and HOMA-IR score. Consumption of calcium supplement plus low-dose aspirin resulted in a significant difference serum hs-CRP levels as compared to the placebo (102.87 vs. 3227.75 ng mL(-1), p = 0.01). Also, mean changes for plasma TAC (68.96 vs. -74.46 mmol L(-1), p = 0.04) and total GSH levels (304.33 vs. -39.33 micromol L(-1), p = 0.03) were significantly different between the two groups. No significant differences were found comparing calcium supplement plus low-dose aspirin and placebo in terms of their effects on FPG, serum insulin levels and HOMA-IR. Within-group differences in the placebo group revealed a significant increase in serum hs-CRP levels (3227.75 ng mL(-1), p = 0.008) and marginally significant increase in plasma total GSH levels (304.33 micromol L(-1), p = 0.07). In conclusion, consumption calcium supplement plus low-dose aspirin during pregnancy for 9 weeks in pregnant women at risk for pre-eclampsia resulted in a significant difference serum hs-CRP and increased levels of plasma TAC and total GSH as compared to the placebo group, but could not affect serum insulin levels and HOMA-IR score." @default.
• W2316971979 created "2016-06-24" @default.
• W2316971979 creator A5000815256 @default.
• W2316971979 creator A5010600173 @default.
• W2316971979 creator A5043181915 @default.
• W2316971979 creator A5065652905 @default.
• W2316971979 creator A5071844774 @default.
• W2316971979 date "2012-05-01" @default.
• W2316971979 modified "2023-10-14" @default.
• W2316971979 title "A Randomized Controlled Clinical Trial Investigating the Effect of Calcium Supplement Plus Low-dose Aspirin on hs-CRP, Oxidative Stress and Insulin Resistance in Pregnant Women at Risk for Pre-eclampsia" @default.
• W2316971979 cites W1979283323 @default.
• W2316971979 cites W1984970610 @default.
• W2316971979 cites W1999349182 @default.
• W2316971979 cites W2002393890 @default.
• W2316971979 cites W2005646325 @default.
• W2316971979 cites W2016598747 @default.
• W2316971979 cites W2019741032 @default.
• W2316971979 cites W2033718750 @default.
• W2316971979 cites W2048161073 @default.
• W2316971979 cites W2050075340 @default.
• W2316971979 cites W2055717177 @default.
• W2316971979 cites W2068716971 @default.
• W2316971979 cites W2082916190 @default.
• W2316971979 cites W2083188761 @default.
• W2316971979 cites W2086257365 @default.
• W2316971979 cites W2104643018 @default.
• W2316971979 cites W2105494350 @default.
• W2316971979 cites W2112110686 @default.
• W2316971979 cites W2113184924 @default.
• W2316971979 cites W2114457285 @default.
• W2316971979 cites W2125889714 @default.
• W2316971979 cites W2126793605 @default.
• W2316971979 cites W2130148279 @default.
• W2316971979 cites W2131996809 @default.
• W2316971979 cites W2148066150 @default.
• W2316971979 cites W2149595540 @default.
• W2316971979 cites W2152646736 @default.
• W2316971979 cites W2319803423 @default.
• W2316971979 cites W4240513034 @default.
• W2316971979 doi "https://doi.org/10.3923/pjbs.2012.469.476" @default.
• W2316971979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24187901" @default.
• W2316971979 hasPublicationYear "2012" @default.
• W2316971979 type Work @default.
• W2316971979 sameAs 2316971979 @default.
• W2316971979 citedByCount "8" @default.
• W2316971979 countsByYear W23169719792014 @default.
• W2316971979 countsByYear W23169719792015 @default.
• W2316971979 countsByYear W23169719792017 @default.
• W2316971979 countsByYear W23169719792019 @default.
• W2316971979 countsByYear W23169719792020 @default.
• W2316971979 countsByYear W23169719792022 @default.
• W2316971979 countsByYear W23169719792023 @default.
• W2316971979 crossrefType "journal-article" @default.
• W2316971979 hasAuthorship W2316971979A5000815256 @default.
• W2316971979 hasAuthorship W2316971979A5010600173 @default.
• W2316971979 hasAuthorship W2316971979A5043181915 @default.
• W2316971979 hasAuthorship W2316971979A5065652905 @default.
• W2316971979 hasAuthorship W2316971979A5071844774 @default.
• W2316971979 hasConcept C126322002 @default.
• W2316971979 hasConcept C134018914 @default.
• W2316971979 hasConcept C142724271 @default.
• W2316971979 hasConcept C204787440 @default.
• W2316971979 hasConcept C27081682 @default.
• W2316971979 hasConcept C2776151105 @default.
• W2316971979 hasConcept C2777218350 @default.
• W2316971979 hasConcept C2777391703 @default.
• W2316971979 hasConcept C2777628954 @default.
• W2316971979 hasConcept C2779234561 @default.
• W2316971979 hasConcept C2779306644 @default.
• W2316971979 hasConcept C2781276381 @default.
• W2316971979 hasConcept C519063684 @default.
• W2316971979 hasConcept C54355233 @default.
• W2316971979 hasConcept C555293320 @default.
• W2316971979 hasConcept C71924100 @default.
• W2316971979 hasConcept C86803240 @default.
• W2316971979 hasConceptScore W2316971979C126322002 @default.
• W2316971979 hasConceptScore W2316971979C134018914 @default.
• W2316971979 hasConceptScore W2316971979C142724271 @default.
• W2316971979 hasConceptScore W2316971979C204787440 @default.
• W2316971979 hasConceptScore W2316971979C27081682 @default.
• W2316971979 hasConceptScore W2316971979C2776151105 @default.
• W2316971979 hasConceptScore W2316971979C2777218350 @default.
• W2316971979 hasConceptScore W2316971979C2777391703 @default.
• W2316971979 hasConceptScore W2316971979C2777628954 @default.
• W2316971979 hasConceptScore W2316971979C2779234561 @default.
• W2316971979 hasConceptScore W2316971979C2779306644 @default.
• W2316971979 hasConceptScore W2316971979C2781276381 @default.
• W2316971979 hasConceptScore W2316971979C519063684 @default.
• W2316971979 hasConceptScore W2316971979C54355233 @default.
• W2316971979 hasConceptScore W2316971979C555293320 @default.
• W2316971979 hasConceptScore W2316971979C71924100 @default.
• W2316971979 hasConceptScore W2316971979C86803240 @default.
• W2316971979 hasIssue "10" @default.
• W2316971979 hasLocation W23169719791 @default.
• W2316971979 hasLocation W23169719792 @default.
• W2316971979 hasOpenAccess W2316971979 @default.
• W2316971979 hasPrimaryLocation W23169719791 @default.
• W2316971979 hasRelatedWork W124733979 @default.

• next