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- W2316990249 abstract "Over recent years, investigators have experienced a growing appreciation for small airways disease as an occupational lung disease. Small airways disease includes a range of diagnoses such as hypersensitivity pneumonitis, mineral dust airways disease, and constrictive bronchiolitis. Novel exposures or, in certain cases, novel settings for well-established respiratory toxicants continue to be reported. Given recent reports among military personnel serving in the Middle East as well as diacetyl exposed workers employed in microwave popcorn manufacturing plants, constrictive bronchiolitis as an occupational lung disease has gained particular notoriety. The diagnosis of constrictive bronchiolitis remains challenging as plain chest radiographs may appear normal and physiologic testing may reveal an obstructive ventilatory defect suggesting asthma. Diagnostic workup of small airways disease includes high-resolution chest computed tomography scan with inspiratory and expiratory imaging and pulmonary function testing. Tissue diagnosis may be unnecessary in the compatible exposure scenario. Identification of exposure and subsequent exposure cessation remains a cornerstone of treatment for the affected individual as well as prevention for co-workers sharing similar exposures. Whereas exposure cessation may lead to improvement of disease in certain affected individuals, corticosteroid therapy may be required in recalcitrant cases; unfortunately, individuals such as patients with chronic hypersensitivity pneumonitis or constrictive bronchiolitis may fail to respond to corticosteroid therapy." @default.
- W2316990249 created "2016-06-24" @default.
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- W2316990249 date "2015-05-01" @default.
- W2316990249 modified "2023-09-27" @default.
- W2316990249 title "Small Airways Disease Related to Occupational Exposures" @default.
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