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• W2316995355 abstract "You have accessJournal of UrologyImaging/Radiology: Uroradiology II1 Apr 2016PD06-12 ADDITION OF ULTRASOUND BLADDER IMAGING DURING URODYNAMICS TO CALCULATE DETRUSOR WALL TENSION AND STRESS Anna Nagle, Adam Klausner, Andrew Colhoun, Paul Ratz, Wayne Barbee, Laura Carucci, and John Speich Anna NagleAnna Nagle More articles by this author , Adam KlausnerAdam Klausner More articles by this author , Andrew ColhounAndrew Colhoun More articles by this author , Paul RatzPaul Ratz More articles by this author , Wayne BarbeeWayne Barbee More articles by this author , Laura CarucciLaura Carucci More articles by this author , and John SpeichJohn Speich More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2632AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES During standard urodynamics, vesical pressure (Pves) generally increases little during bladder filling. Furthermore, afferent nerve signaling reflects detrusor wall tension rather than pressure. Thus, there is a pressing need for a urodynamics test that evaluates detrusor wall tension. The purpose of this investigation was to describe a novel method to determine detrusor wall tension during urodynamics through the incorporation of ultrasound imaging. METHODS As part of an institutional review board approved urodynamics protocol, an individual with overactive bladder (OAB) underwent ultrasound imaging during filling. The fill rate was 10% cystometric capacity (Ccap) as determined by an initial fill. Ultrasound images were obtained by an ultrasound technologist using a Philips Epic 7 machine with an abdominal probe at frequency of 1 to 5 MHz. The probe was held in a constant position throughout filling and captured midsagittal and transverse images at 1 min intervals. Using acquired ultrasound image data and vesical pressure, we developed an objective technique to calculate detrusor wall tension, wall stress, and wall compliance (Fig 1a-b). From each cross-sectional image, we measured luminal and wall areas and perimeters (Fig. 1c-d). In the sagittal and transverse directions, wall tension was calculated as Pves*luminal area, wall stress as wall tension/wall area, and strain as the change in inner perimeter/inner perimeter at 10%Ccap (Fig 1a-b). Sagittal compliance was calculated as sagittal strain/transverse stress and transverse compliance was the transverse strain/sagittal stress. RESULTS Pves was relatively flat during filling, wall stress increased linearly, and compliance decreased exponentially (Fig. 1e-g). This finding demonstrates that Pves measurements during urodynamics do not necessarily reflect the underlying state of detrusor wall tension. CONCLUSIONS This study demonstrates that detrusor wall tension, wall stress, and wall compliance can be calculated by adding ultrasound imaging to standard urodynamics. This technique may be useful in the diagnosis and treatment of OAB and other disorders of voiding dysfunction. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e179 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Anna Nagle More articles by this author Adam Klausner More articles by this author Andrew Colhoun More articles by this author Paul Ratz More articles by this author Wayne Barbee More articles by this author Laura Carucci More articles by this author John Speich More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W2316995355 title "PD06-12 ADDITION OF ULTRASOUND BLADDER IMAGING DURING URODYNAMICS TO CALCULATE DETRUSOR WALL TENSION AND STRESS" @default.
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