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- W2317005429 abstract "We quantified the effect of heparin sodium as a sample anticoagulant on the measurement of sodium, potassium, and ionized calcium values in whole blood and quality control material. Twenty-five- to 100-μL volumes of heparin had a negligible effect on sample values for sodium and potassium. For ionized calcium, 50 μL or greater of 1,000 U/mL of heparin sodium ( United States Pharmacopeia ) added to the samples resulted in sufficiently large differences from the control value (up to 0.36 mmol/L for the quality control material and 0.16 mmol/L for whole blood) that could have been interpreted as clinically significant. The smallest difference from the control value (0.05 mmol/L for the quality control material and 0.02 mmol/L for whole blood) occurred with 25 μL of 100 U/mL of heparin sodium. We describe a technique for preparing heparinized syringes with a residual volume of heparin that is adequate for blood specimen anticoagulation, but insufficient to result in clinically significant effects on blood sodium, potassium, and ionized calcium measurements. The mean volume of residual heparin in syringes prepared by respiratory therapists familiar with this technique was 19±9 μL." @default.
- W2317005429 created "2016-06-24" @default.
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- W2317005429 date "1992-04-01" @default.
- W2317005429 modified "2023-09-27" @default.
- W2317005429 title "Effect of Heparin on Corning 288 Measurement of Sodium, Potassium, and Ionized Calcium" @default.
- W2317005429 doi "https://doi.org/10.1093/labmed/23.4.249" @default.
- W2317005429 hasPublicationYear "1992" @default.
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