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- W2317110260 abstract "Introduction Evidence exists to suggest that the symptoms of pre-eclampsia are mediated by an imbalance of circulating angiogenic factors of placental origin; reduced concentrations of placental growth factor (PlGF) have been correlated with disease severity. Methods A prospective, observational, cohort study was undertaken in seven UK maternity units. Women presenting 20 + 0 to 40 + 6 weeks gestation with suspected pre-eclampsia had serum PlGF measurement. ISSHP definitions of hypertensive disease were assigned, blinded to PlGF values. Analysis of the enrolment sample was conducted to evaluate diagnostic accuracy for pre-eclampsia requiring delivery within 14 days for very low PlGF ( 12 pg/ml 5th centile) as referent. Results Diagnosis of pre-eclampsia requiring delivery within 14 days using 5th centile as threshold. Conclusion In women presenting" @default.
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- W2317110260 date "2013-04-01" @default.
- W2317110260 modified "2023-09-24" @default.
- W2317110260 title "2.2 Plasma Placental Growth Factor (PlGF) in the Diagnosis of Women with Pre-Eclampsia Requiring Delivery Within 14 Days: The PELICAN Study: Abstract 2.2 Table" @default.
- W2317110260 doi "https://doi.org/10.1136/archdischild-2013-303966.005" @default.
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