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- W2317133608 abstract "Three new tigliane-type diterpenoids were isolated from the methanolic extract of the twigs and leaves of Croton caudatus, trivially named crotusins A-C (1-3). The structures of compounds 1-3 were elucidated on the basis of extensive spectral methods. These new compounds were highly oxygenated and heavily substituted. Cytotoxic activity against five human tumor cell lines was assessed for compounds 1-3 of which compound 3 showed significant inhibitory activity with IC50 values ranging from 0.49 to 4.19 µM against these cells, while crotusins A and B exhibited moderate activity." @default.
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- W2317133608 date "2016-03-22" @default.
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- W2317133608 title "New Cytotoxic Tigliane Diterpenoids from Croton caudatus" @default.
- W2317133608 doi "https://doi.org/10.1055/s-0042-102539" @default.
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