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• W2317258715 abstract "Six new quinone sesquiterpenes, myrothecols A–F (1–6), and hymenopsin B (7) were isolated from cultures of Myrothecium sp. SC0265 by bioassay-guided fractionation. Their structures were elucidated on the basis of 1D and 2D NMR and MS data. The absolute configurations of the new compounds were assigned by CD/TDDFT calculations, and that of and hymenopsin B was confirmed by X-ray diffraction analysis. Compounds 1–5 and hymenopsin demonstrated cytotoxic activity against human carcinoma A549, HeLa, and HepG2 cells. Compounds 1–5 also exhibited antibacterial activity against Staphylococcus aureus and Bacillus cereus." @default.
• W2317258715 created "2016-06-24" @default.
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• W2317258715 date "2014-08-04" @default.
• W2317258715 modified "2023-10-16" @default.
• W2317258715 title "Cytotoxic and Antibacterial Quinone Sesquiterpenes from a <i>Myrothecium</i> Fungus" @default.
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• W2317258715 doi "https://doi.org/10.1021/np500142g" @default.
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