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- W2317384735 abstract "Precipitin specifically reacted with saline extract from cancer tissue of human stomach and colon was produced in rabbit sera immunized with extract of gastric cancer. Cancer specific precipitation reaction was demonstrated by ring test with anti-gastric cancer immune rabbit serum absorbed with pooled human plasma and extracts of normal gastric linings. The reaction was inhibited by glucosamine and galactosamine as simple sugars and urine from gastric cancer patients, but not inhibited by extracts from fetal stomach, liver, intestine and kidney. Single precipitin band was observed in agar gel and immuno-electrophoresis between extract of gastric cancer and IgG fraction of anti-gastric cancer rabbit serum.Purified antigenic substance was prepared by alcohol precipitation of saline extract of gastric cancer tissue followed by DEAE-cellulose colmn chromatography and polyacrylamide gel electrophoresis. From the chemical examination, main component of the antigenic substance proved to be a protein. The antigenic activity was lost by the action of pepsin and pronase." @default.
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- W2317384735 date "1972-01-01" @default.
- W2317384735 modified "2023-10-03" @default.
- W2317384735 title "IMMUNOCHEMICAL STUDIES ON CANCER" @default.
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- W2317384735 doi "https://doi.org/10.2974/kmj1951.22.235" @default.
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