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- W2317431908 abstract "Increasing evidence suggests that acute or chronic exercise has significant effects on insomnia. However, the mechanisms underlying neural function of physical activity on the sleep functions are still unclear. The present study was designed to verify the effect of acute treadmill exercise on sleep in mice. Male ICR mice (10 weeks old) were subjected to a single bout of running (at the speed of 100 rpm/min) for 0, 5, 15, 30, or 60 minutes at the beginning of the light phase. In order to unify the duration of sleep deprivation, mice in each group were deprived sleep during non-running period (for up to 90 minutes). After the running, sleep was recorded for 14 hours. Mice running for 5 or 15 minutes showed no difference in following sleep. Mice with running for 30 minutes showed remarkable increase in the amount of non-rapid eye movement (NREM) sleep and enhanced slow-wave activity (SWA) during NREM sleep. Plasma concentration of ketone bodies (acetoacetate and β-hydroxybutyrate) in mice with running for 30 minutes were increased compared with that of 15-mitutes running or control (only sleep-deprived/non-treated) mice. These findings suggest that acute exercise induces longer and deeper sleep and enhance the ketone body production." @default.
- W2317431908 created "2016-06-24" @default.
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- W2317431908 date "2015-04-01" @default.
- W2317431908 modified "2023-09-23" @default.
- W2317431908 title "Exercise enhances following sleep in mice" @default.
- W2317431908 doi "https://doi.org/10.1096/fasebj.29.1_supplement.840.3" @default.
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