FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2317502808> ?p ?o ?g. }

• W2317502808 endingPage "68" @default.
• W2317502808 startingPage "59" @default.
• W2317502808 abstract "Micrurus snakebites can cause death by muscle paralysis and respiratory arrest a few hours after envenomation. The specific treatment for these snake envenomations is the intravenous application of heterologous antivenom. In Brazil, this antivenom is produced from horses that are immunized with a mixture of Micrurus corallinus and Micrurus frontalis venoms, which are snakes that inhabit the south and southeastern regions of the country. Previously, we demonstrated that the coral antivenom, which is used in human therapy, was not able to neutralize several of the toxic venom effects from some Micrurus species that inhabit the country, as measured by in vitro and in vivo assays. The present study aimed to investigate the immunogenic properties of Micrurus spp. venoms, as well as the cross-reactivity and neutralization potential of experimental monovalent and polyvalent sera that were produced in different animal species. The present data showed that Micrurus venoms exhibited the same immunogenicity pattern in the three utilized animal species and that the specific antisera presented a large cross-reactivity when analyzed with ELISA and Western blot assays. Nonetheless, these positive results were not well correlated with the neutralizing potential of the antisera. Thus, the establishment of a new antigenic mixture to produce novel more efficient therapeutic Micrurus antivenom is not a simple task. Further studies, particularly with the Micrurus lemniscatus, Micrurus altirostris and Micrurus surinamensis venoms, are necessary to establish new strategies for the production of antivenoms with broad neutralizing activity for the treatment of accidents involving coral snakes throughout the country." @default.
• W2317502808 created "2016-06-24" @default.
• W2317502808 creator A5002375467 @default.
• W2317502808 creator A5035151105 @default.
• W2317502808 creator A5038911096 @default.
• W2317502808 creator A5044260371 @default.
• W2317502808 creator A5044855067 @default.
• W2317502808 creator A5054895441 @default.
• W2317502808 date "2016-07-01" @default.
• W2317502808 modified "2023-10-06" @default.
• W2317502808 title "Micrurus snake species: Venom immunogenicity, antiserum cross-reactivity and neutralization potential" @default.
• W2317502808 cites W1924951043 @default.
• W2317502808 cites W1975822761 @default.
• W2317502808 cites W1977544151 @default.
• W2317502808 cites W1992234328 @default.
• W2317502808 cites W2001616870 @default.
• W2317502808 cites W2005146709 @default.
• W2317502808 cites W2007639922 @default.
• W2317502808 cites W2009463493 @default.
• W2317502808 cites W2019056589 @default.
• W2317502808 cites W2035074554 @default.
• W2317502808 cites W2035571656 @default.
• W2317502808 cites W2064799933 @default.
• W2317502808 cites W2066116350 @default.
• W2317502808 cites W2070464822 @default.
• W2317502808 cites W2076916983 @default.
• W2317502808 cites W2099925238 @default.
• W2317502808 cites W2100837269 @default.
• W2317502808 cites W2101108802 @default.
• W2317502808 cites W2122755814 @default.
• W2317502808 cites W2128247024 @default.
• W2317502808 cites W2170802564 @default.
• W2317502808 cites W2246714120 @default.
• W2317502808 cites W2280618533 @default.
• W2317502808 cites W2417078657 @default.
• W2317502808 doi "https://doi.org/10.1016/j.toxicon.2016.03.020" @default.
• W2317502808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27045363" @default.
• W2317502808 hasPublicationYear "2016" @default.
• W2317502808 type Work @default.
• W2317502808 sameAs 2317502808 @default.
• W2317502808 citedByCount "28" @default.
• W2317502808 countsByYear W23175028082016 @default.
• W2317502808 countsByYear W23175028082017 @default.
• W2317502808 countsByYear W23175028082018 @default.
• W2317502808 countsByYear W23175028082019 @default.
• W2317502808 countsByYear W23175028082020 @default.
• W2317502808 countsByYear W23175028082021 @default.
• W2317502808 countsByYear W23175028082022 @default.
• W2317502808 countsByYear W23175028082023 @default.
• W2317502808 crossrefType "journal-article" @default.
• W2317502808 hasAuthorship W2317502808A5002375467 @default.
• W2317502808 hasAuthorship W2317502808A5035151105 @default.
• W2317502808 hasAuthorship W2317502808A5038911096 @default.
• W2317502808 hasAuthorship W2317502808A5044260371 @default.
• W2317502808 hasAuthorship W2317502808A5044855067 @default.
• W2317502808 hasAuthorship W2317502808A5054895441 @default.
• W2317502808 hasConcept C117287731 @default.
• W2317502808 hasConcept C14086860 @default.
• W2317502808 hasConcept C145600735 @default.
• W2317502808 hasConcept C147483822 @default.
• W2317502808 hasConcept C159047783 @default.
• W2317502808 hasConcept C18903297 @default.
• W2317502808 hasConcept C203014093 @default.
• W2317502808 hasConcept C2522874641 @default.
• W2317502808 hasConcept C2779448229 @default.
• W2317502808 hasConcept C2780868878 @default.
• W2317502808 hasConcept C86803240 @default.
• W2317502808 hasConcept C90856448 @default.
• W2317502808 hasConcept C91523082 @default.
• W2317502808 hasConceptScore W2317502808C117287731 @default.
• W2317502808 hasConceptScore W2317502808C14086860 @default.
• W2317502808 hasConceptScore W2317502808C145600735 @default.
• W2317502808 hasConceptScore W2317502808C147483822 @default.
• W2317502808 hasConceptScore W2317502808C159047783 @default.
• W2317502808 hasConceptScore W2317502808C18903297 @default.
• W2317502808 hasConceptScore W2317502808C203014093 @default.
• W2317502808 hasConceptScore W2317502808C2522874641 @default.
• W2317502808 hasConceptScore W2317502808C2779448229 @default.
• W2317502808 hasConceptScore W2317502808C2780868878 @default.
• W2317502808 hasConceptScore W2317502808C86803240 @default.
• W2317502808 hasConceptScore W2317502808C90856448 @default.
• W2317502808 hasConceptScore W2317502808C91523082 @default.
• W2317502808 hasFunder F4320320997 @default.
• W2317502808 hasLocation W23175028081 @default.
• W2317502808 hasLocation W23175028082 @default.
• W2317502808 hasOpenAccess W2317502808 @default.
• W2317502808 hasPrimaryLocation W23175028081 @default.
• W2317502808 hasRelatedWork W1993558161 @default.
• W2317502808 hasRelatedWork W2031644913 @default.
• W2317502808 hasRelatedWork W2039037695 @default.
• W2317502808 hasRelatedWork W2061565150 @default.
• W2317502808 hasRelatedWork W2391653693 @default.
• W2317502808 hasRelatedWork W2762951026 @default.
• W2317502808 hasRelatedWork W2766958547 @default.
• W2317502808 hasRelatedWork W3040911294 @default.
• W2317502808 hasRelatedWork W3214954676 @default.
• W2317502808 hasRelatedWork W4220854187 @default.
• W2317502808 hasVolume "117" @default.

• next