Matches in SemOpenAlex for { <https://semopenalex.org/work/W2317506046> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2317506046 abstract "Abstract Experimental evolution is an important research method that allows for the study of evolutionary processes occurring in microorganisms. Here we present a novel approach to experimental evolution that is based on application of next generation sequencing. Under this approach population level sequencing is applied to an evolving population in which multiple first-step beneficial mutations occur concurrently. As a result, frequencies of multiple beneficial mutations are observed in each replicate of an experiment. For this new type of data we develop methods of statistical inference. In particular, we propose a method for imputing selection coefficients of first-step beneficial mutations. The imputed selection coefficient are then used for testing the distribution of first-step beneficial mutations and for estimation of mean selection coefficient. In the case when selection coefficients are uniformly distributed, collected data may also be used to estimate the total number of available first-step beneficial mutations." @default.
- W2317506046 created "2016-06-24" @default.
- W2317506046 creator A5022039008 @default.
- W2317506046 creator A5050086795 @default.
- W2317506046 creator A5062248776 @default.
- W2317506046 date "2015-01-01" @default.
- W2317506046 modified "2023-09-24" @default.
- W2317506046 title "Inference for one-step beneficial mutations using next generation sequencing" @default.
- W2317506046 cites W1964170829 @default.
- W2317506046 cites W1977852064 @default.
- W2317506046 cites W1988057380 @default.
- W2317506046 cites W2003393395 @default.
- W2317506046 cites W2036005222 @default.
- W2317506046 cites W2055346334 @default.
- W2317506046 cites W2065112092 @default.
- W2317506046 cites W2072290177 @default.
- W2317506046 cites W2087808706 @default.
- W2317506046 cites W2110455575 @default.
- W2317506046 cites W2114810739 @default.
- W2317506046 cites W2115583744 @default.
- W2317506046 cites W2117428236 @default.
- W2317506046 cites W2117737648 @default.
- W2317506046 cites W2142391696 @default.
- W2317506046 cites W2143271868 @default.
- W2317506046 cites W2144386534 @default.
- W2317506046 cites W2152177323 @default.
- W2317506046 cites W4239648059 @default.
- W2317506046 doi "https://doi.org/10.1515/sagmb-2014-0030" @default.
- W2317506046 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5563372" @default.
- W2317506046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25720101" @default.
- W2317506046 hasPublicationYear "2015" @default.
- W2317506046 type Work @default.
- W2317506046 sameAs 2317506046 @default.
- W2317506046 citedByCount "0" @default.
- W2317506046 crossrefType "journal-article" @default.
- W2317506046 hasAuthorship W2317506046A5022039008 @default.
- W2317506046 hasAuthorship W2317506046A5050086795 @default.
- W2317506046 hasAuthorship W2317506046A5062248776 @default.
- W2317506046 hasBestOaLocation W23175060462 @default.
- W2317506046 hasConcept C104317684 @default.
- W2317506046 hasConcept C105795698 @default.
- W2317506046 hasConcept C119857082 @default.
- W2317506046 hasConcept C144024400 @default.
- W2317506046 hasConcept C149923435 @default.
- W2317506046 hasConcept C154945302 @default.
- W2317506046 hasConcept C2776214188 @default.
- W2317506046 hasConcept C2781162219 @default.
- W2317506046 hasConcept C2908647359 @default.
- W2317506046 hasConcept C33923547 @default.
- W2317506046 hasConcept C41008148 @default.
- W2317506046 hasConcept C501734568 @default.
- W2317506046 hasConcept C51679486 @default.
- W2317506046 hasConcept C54355233 @default.
- W2317506046 hasConcept C81917197 @default.
- W2317506046 hasConcept C86803240 @default.
- W2317506046 hasConceptScore W2317506046C104317684 @default.
- W2317506046 hasConceptScore W2317506046C105795698 @default.
- W2317506046 hasConceptScore W2317506046C119857082 @default.
- W2317506046 hasConceptScore W2317506046C144024400 @default.
- W2317506046 hasConceptScore W2317506046C149923435 @default.
- W2317506046 hasConceptScore W2317506046C154945302 @default.
- W2317506046 hasConceptScore W2317506046C2776214188 @default.
- W2317506046 hasConceptScore W2317506046C2781162219 @default.
- W2317506046 hasConceptScore W2317506046C2908647359 @default.
- W2317506046 hasConceptScore W2317506046C33923547 @default.
- W2317506046 hasConceptScore W2317506046C41008148 @default.
- W2317506046 hasConceptScore W2317506046C501734568 @default.
- W2317506046 hasConceptScore W2317506046C51679486 @default.
- W2317506046 hasConceptScore W2317506046C54355233 @default.
- W2317506046 hasConceptScore W2317506046C81917197 @default.
- W2317506046 hasConceptScore W2317506046C86803240 @default.
- W2317506046 hasIssue "1" @default.
- W2317506046 hasLocation W23175060461 @default.
- W2317506046 hasLocation W23175060462 @default.
- W2317506046 hasLocation W23175060463 @default.
- W2317506046 hasLocation W23175060464 @default.
- W2317506046 hasOpenAccess W2317506046 @default.
- W2317506046 hasPrimaryLocation W23175060461 @default.
- W2317506046 hasRelatedWork W1965062432 @default.
- W2317506046 hasRelatedWork W1994925979 @default.
- W2317506046 hasRelatedWork W2027998578 @default.
- W2317506046 hasRelatedWork W2047059769 @default.
- W2317506046 hasRelatedWork W2099509294 @default.
- W2317506046 hasRelatedWork W211288168 @default.
- W2317506046 hasRelatedWork W2126676149 @default.
- W2317506046 hasRelatedWork W2152022752 @default.
- W2317506046 hasRelatedWork W2262006598 @default.
- W2317506046 hasRelatedWork W2272531061 @default.
- W2317506046 hasVolume "14" @default.
- W2317506046 isParatext "false" @default.
- W2317506046 isRetracted "false" @default.
- W2317506046 magId "2317506046" @default.
- W2317506046 workType "article" @default.