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- W2317532829 abstract "Objective The aim of this study was to evaluate the effect of chlamydial infection and microbial flora in cervical mucus at the time of embryo transfer (ET) on fertilization and implantation in women undergoing intracytoplasmic sperm injection procedures. Participants and methods A total of 500 infertile women were enrolled in this study. All were recruited from the outpatient clinic of the Assisted Reproduction Unit in International Islamic Centre for Population Studies and Researches, Al Azhar University. All participants underwent pituitary downregulation using either a long or a short protocol, followed by ovarian stimulation, oocytes retrieval, fertilization, and embryos transfer. In the study group, cervical swabs were taken with the first folliculometry and screened for chlamydia and other bacterial growth; antibiotics were administered accordingly for positive cases. During ET, cervical swabs were taken from the control group and tested for chlamydia and other bacterial infections, but with no use of any antimicrobials; pregnancy tests were performed two weeks after ET and the participants were accordingly divided into two subgroups: a pregnant group and a nonpregnant group. Results The overall incidence of pregnancy was 193/500 (38.6%), and for those who were pregnant, the incidence of chlamydia alone (in the study group) was 8.89% compared with 8.74% (in the control group). The incidence of other bacterial growth (in the study group) was 35.56% compared with 30.1% (in the control group). The incidence of associated chlamydia and other bacterial growth (in the study group) was 8.89% compared with 5.83% (in the control group). Conclusion Chlamydial infection and microbial flora of the cervix detected during ET play no role in the implantation process and do not affect pregnancy rates significantly in women undergoing intracytoplasmic sperm injection, and antimicrobial plays no significant role in improving the outcome of the rate of pregnancy." @default.
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- W2317532829 date "2014-05-01" @default.
- W2317532829 modified "2023-09-26" @default.
- W2317532829 title "Evaluation of the effect of bacterial colonization in cervical mucus on the outcome of intracytoplasmic sperm injection cycles" @default.
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- W2317532829 doi "https://doi.org/10.1097/01.ebx.0000440890.92323.cc" @default.
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