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- W2317582931 abstract "Condensation reactions of enantiopure bis-3,4-diazaphospholanes (BDPs) that are functionalized with carboxylic acids enable covalent attachment to bead and silica supports. Exposure of tethered BDPs to the hydroformylation catalyst precursor, Rh(acac)(CO)2, yields catalysts for immobilized asymmetric hydroformylation (iAHF) of prochiral alkenes. Compared with homogeneous catalysts, catalysts immobilized on Tentagel resins exhibit similarly high regioselectivity and enantioselectivity. When corrected for apparent catalyst loading, the activity of the immobilized catalysts approaches that of the homogeneous analogues. Excellent recyclability with trace levels of rhodium leaching are observed in batch and flow reactor conditions. Silica-bound catalysts exhibit poorer enantioselectivities." @default.
- W2317582931 created "2016-06-24" @default.
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- W2317582931 date "2014-05-20" @default.
- W2317582931 modified "2023-10-08" @default.
- W2317582931 title "Immobilized Bisdiazaphospholane Catalysts for Asymmetric Hydroformylation" @default.
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- W2317582931 doi "https://doi.org/10.1021/ja501568k" @default.
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