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- W2317641570 abstract "Investigators studying the infectious protein (prion protein, PrP) have long sought a sensitive and minimally invasive diagnostic tool that is specifically targeted to the particular protein that causes the disease. For all forms of Creutzfeldt–Jakob disease — sporadic, inherited, and acquired — such diagnostic tools are emerging, as illustrated by two similar technologies now reported in the Journal by Orrú et al.1 and Moda et al.2: a real-time quaking (shaking)-induced conversion (RT-QuIC) assay applied to nasal olfactory epithelial brushings1 and a sonicated protein misfolding cyclic amplification (PMCA) assay applied to urine.2 Both assays rely on imparting kinetic energy into . . ." @default.
- W2317641570 created "2016-06-24" @default.
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- W2317641570 date "2014-08-07" @default.
- W2317641570 modified "2023-10-17" @default.
- W2317641570 title "Shaken, Not Sonicated?" @default.
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- W2317641570 doi "https://doi.org/10.1056/nejme1407419" @default.
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