Matches in SemOpenAlex for { <https://semopenalex.org/work/W2317692702> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2317692702 endingPage "422" @default.
- W2317692702 startingPage "417" @default.
- W2317692702 abstract "Developing highly selective probes for subcellular regions such as nucleus and cytoplamic organelles is of great interest for cellular imaging and high content screening analysis for biology and medicine. Cytoplasmic delivery of QDs has been well-understood, while nuclear delivery of QDs has been a challenge due to the unique structural characteristics of cell nucleus. In this study, we systematically investigated nucleus penetrating properties of small-sized ligand-exchanged QDs with either positive or negative surface charges in the similar size range of hydrodynamic diameter (7-10 nm). We found that the positively-charged QDs efficiently stain the nucleus in fixed HeLa cells as well as label nucleolar compartments in live HeLa cells. In contrast, the negatively charged QDs with the similar size range stain only the cytoplam in either fixed or live cells. The charge-dependent labeling pattern allowed us to simultaneously perform multiplex imaging of nuclues and cytoplasm. This study offers an insight into efficient nuclear delivery of nanoparticles such as QDs of which surface charge and size are critical for intracelllar localization and delivery." @default.
- W2317692702 created "2016-06-24" @default.
- W2317692702 creator A5004550953 @default.
- W2317692702 creator A5032666703 @default.
- W2317692702 creator A5055248784 @default.
- W2317692702 creator A5068596405 @default.
- W2317692702 date "2013-01-01" @default.
- W2317692702 modified "2023-09-27" @default.
- W2317692702 title "Selective Targeting of Cellular Nucleus Using Positively-Charged Quantum Dots" @default.
- W2317692702 doi "https://doi.org/10.1166/jnn.2013.6917" @default.
- W2317692702 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23646748" @default.
- W2317692702 hasPublicationYear "2013" @default.
- W2317692702 type Work @default.
- W2317692702 sameAs 2317692702 @default.
- W2317692702 citedByCount "10" @default.
- W2317692702 countsByYear W23176927022013 @default.
- W2317692702 countsByYear W23176927022015 @default.
- W2317692702 countsByYear W23176927022019 @default.
- W2317692702 countsByYear W23176927022020 @default.
- W2317692702 countsByYear W23176927022021 @default.
- W2317692702 countsByYear W23176927022022 @default.
- W2317692702 countsByYear W23176927022023 @default.
- W2317692702 crossrefType "journal-article" @default.
- W2317692702 hasAuthorship W2317692702A5004550953 @default.
- W2317692702 hasAuthorship W2317692702A5032666703 @default.
- W2317692702 hasAuthorship W2317692702A5055248784 @default.
- W2317692702 hasAuthorship W2317692702A5068596405 @default.
- W2317692702 hasConcept C124657808 @default.
- W2317692702 hasConcept C12554922 @default.
- W2317692702 hasConcept C147789679 @default.
- W2317692702 hasConcept C1491633281 @default.
- W2317692702 hasConcept C15526883 @default.
- W2317692702 hasConcept C168240541 @default.
- W2317692702 hasConcept C171250308 @default.
- W2317692702 hasConcept C185592680 @default.
- W2317692702 hasConcept C190062978 @default.
- W2317692702 hasConcept C192562407 @default.
- W2317692702 hasConcept C2777366897 @default.
- W2317692702 hasConcept C2780114586 @default.
- W2317692702 hasConcept C2780358262 @default.
- W2317692702 hasConcept C2780723820 @default.
- W2317692702 hasConcept C2781188995 @default.
- W2317692702 hasConcept C2781294515 @default.
- W2317692702 hasConcept C54355233 @default.
- W2317692702 hasConcept C55493867 @default.
- W2317692702 hasConcept C60644358 @default.
- W2317692702 hasConcept C74864618 @default.
- W2317692702 hasConcept C86803240 @default.
- W2317692702 hasConcept C95444343 @default.
- W2317692702 hasConceptScore W2317692702C124657808 @default.
- W2317692702 hasConceptScore W2317692702C12554922 @default.
- W2317692702 hasConceptScore W2317692702C147789679 @default.
- W2317692702 hasConceptScore W2317692702C1491633281 @default.
- W2317692702 hasConceptScore W2317692702C15526883 @default.
- W2317692702 hasConceptScore W2317692702C168240541 @default.
- W2317692702 hasConceptScore W2317692702C171250308 @default.
- W2317692702 hasConceptScore W2317692702C185592680 @default.
- W2317692702 hasConceptScore W2317692702C190062978 @default.
- W2317692702 hasConceptScore W2317692702C192562407 @default.
- W2317692702 hasConceptScore W2317692702C2777366897 @default.
- W2317692702 hasConceptScore W2317692702C2780114586 @default.
- W2317692702 hasConceptScore W2317692702C2780358262 @default.
- W2317692702 hasConceptScore W2317692702C2780723820 @default.
- W2317692702 hasConceptScore W2317692702C2781188995 @default.
- W2317692702 hasConceptScore W2317692702C2781294515 @default.
- W2317692702 hasConceptScore W2317692702C54355233 @default.
- W2317692702 hasConceptScore W2317692702C55493867 @default.
- W2317692702 hasConceptScore W2317692702C60644358 @default.
- W2317692702 hasConceptScore W2317692702C74864618 @default.
- W2317692702 hasConceptScore W2317692702C86803240 @default.
- W2317692702 hasConceptScore W2317692702C95444343 @default.
- W2317692702 hasIssue "1" @default.
- W2317692702 hasLocation W23176927021 @default.
- W2317692702 hasLocation W23176927022 @default.
- W2317692702 hasOpenAccess W2317692702 @default.
- W2317692702 hasPrimaryLocation W23176927021 @default.
- W2317692702 hasRelatedWork W1537306286 @default.
- W2317692702 hasRelatedWork W2000469986 @default.
- W2317692702 hasRelatedWork W2072331950 @default.
- W2317692702 hasRelatedWork W2079754948 @default.
- W2317692702 hasRelatedWork W2089790589 @default.
- W2317692702 hasRelatedWork W2140481595 @default.
- W2317692702 hasRelatedWork W2313883810 @default.
- W2317692702 hasRelatedWork W2317692702 @default.
- W2317692702 hasRelatedWork W3090876536 @default.
- W2317692702 hasRelatedWork W35137212 @default.
- W2317692702 hasVolume "13" @default.
- W2317692702 isParatext "false" @default.
- W2317692702 isRetracted "false" @default.
- W2317692702 magId "2317692702" @default.
- W2317692702 workType "article" @default.