Matches in SemOpenAlex for { <https://semopenalex.org/work/W2317695215> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2317695215 abstract "Renal effects of endothelin (ET)-3 have been described in normotensive but not spontaneously hypertensive rats (SHR). Infusion (170 ng/kg/min) of the ETB receptor selective agonists ET-3 and sarafotoxin S6c (SS6c) was used to investigate ETB receptor modulation of renal function in SHR. ET-3 decreased glomerular filtration rate (GFR) and renal plasma flow (RPF) by approximately 95% (0.1 +/- 0.01 and 0.1 +/- 0.02 ml/min, respectively) versus vehicle (1.3 +/- 0.08 and 3.6 +/- 0.23, respectively) in SHR. ET-3 exerted a biphasic effect on urine flow (UV); an initial increase and then a decrease (vehicle, 4.2 +/- 0.55; ET-3, 0.2 +/- 0.09 microliter/min). ET-3 increased mean arterial pressure (vehicle, 159 +/- 4.1; ET-3, 174 +/- 3.1 mm Hg). SS6c decreased GFR and RPF by approximately 60% (0.8 +/- 0.12 and 2.0 +/- 0.18 ml/min, respectively) versus vehicle (2.0 +/- 0.19 and 5.2 +/- 0.45, respectively). UV did not change. Depressor effects of SS6c were observed (vehicle, 154 +/- 1.5; SS6c, 127 +/- 3.1 mm Hg). The ETB receptor selective agonists ET-3 and SS6c markedly decreased GFR and RPF in SHR, suggesting that endogenous ET-3 may modulate renal function through ETB receptors in SHR." @default.
- W2317695215 created "2016-06-24" @default.
- W2317695215 creator A5060586573 @default.
- W2317695215 creator A5073278867 @default.
- W2317695215 date "1996-09-01" @default.
- W2317695215 modified "2023-09-26" @default.
- W2317695215 title "Cardiovascular and Renal Effects of Endothelin B Receptor Selective Agonists in Spontaneously Hypertensive Rats" @default.
- W2317695215 cites W1513266031 @default.
- W2317695215 cites W1972551027 @default.
- W2317695215 cites W1974487639 @default.
- W2317695215 cites W1980169310 @default.
- W2317695215 cites W1980762198 @default.
- W2317695215 cites W1985671221 @default.
- W2317695215 cites W1987877866 @default.
- W2317695215 cites W1992176547 @default.
- W2317695215 cites W1996793186 @default.
- W2317695215 cites W2017602773 @default.
- W2317695215 cites W2054733362 @default.
- W2317695215 cites W2055719682 @default.
- W2317695215 cites W2059369537 @default.
- W2317695215 cites W2059742658 @default.
- W2317695215 cites W2062863421 @default.
- W2317695215 cites W2124001677 @default.
- W2317695215 cites W2145622529 @default.
- W2317695215 cites W2151869895 @default.
- W2317695215 cites W1995109288 @default.
- W2317695215 doi "https://doi.org/10.1097/00005344-199609000-00006" @default.
- W2317695215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8877584" @default.
- W2317695215 hasPublicationYear "1996" @default.
- W2317695215 type Work @default.
- W2317695215 sameAs 2317695215 @default.
- W2317695215 citedByCount "3" @default.
- W2317695215 crossrefType "journal-article" @default.
- W2317695215 hasAuthorship W2317695215A5060586573 @default.
- W2317695215 hasAuthorship W2317695215A5073278867 @default.
- W2317695215 hasConcept C119584498 @default.
- W2317695215 hasConcept C126322002 @default.
- W2317695215 hasConcept C134018914 @default.
- W2317695215 hasConcept C142225936 @default.
- W2317695215 hasConcept C144980905 @default.
- W2317695215 hasConcept C149601957 @default.
- W2317695215 hasConcept C159641895 @default.
- W2317695215 hasConcept C170493617 @default.
- W2317695215 hasConcept C185592680 @default.
- W2317695215 hasConcept C2778086073 @default.
- W2317695215 hasConcept C2778938600 @default.
- W2317695215 hasConcept C2779805383 @default.
- W2317695215 hasConcept C2780091579 @default.
- W2317695215 hasConcept C2781073237 @default.
- W2317695215 hasConcept C71924100 @default.
- W2317695215 hasConcept C84393581 @default.
- W2317695215 hasConceptScore W2317695215C119584498 @default.
- W2317695215 hasConceptScore W2317695215C126322002 @default.
- W2317695215 hasConceptScore W2317695215C134018914 @default.
- W2317695215 hasConceptScore W2317695215C142225936 @default.
- W2317695215 hasConceptScore W2317695215C144980905 @default.
- W2317695215 hasConceptScore W2317695215C149601957 @default.
- W2317695215 hasConceptScore W2317695215C159641895 @default.
- W2317695215 hasConceptScore W2317695215C170493617 @default.
- W2317695215 hasConceptScore W2317695215C185592680 @default.
- W2317695215 hasConceptScore W2317695215C2778086073 @default.
- W2317695215 hasConceptScore W2317695215C2778938600 @default.
- W2317695215 hasConceptScore W2317695215C2779805383 @default.
- W2317695215 hasConceptScore W2317695215C2780091579 @default.
- W2317695215 hasConceptScore W2317695215C2781073237 @default.
- W2317695215 hasConceptScore W2317695215C71924100 @default.
- W2317695215 hasConceptScore W2317695215C84393581 @default.
- W2317695215 hasLocation W23176952151 @default.
- W2317695215 hasLocation W23176952152 @default.
- W2317695215 hasOpenAccess W2317695215 @default.
- W2317695215 hasPrimaryLocation W23176952151 @default.
- W2317695215 hasRelatedWork W1968348119 @default.
- W2317695215 hasRelatedWork W1981626491 @default.
- W2317695215 hasRelatedWork W1991914145 @default.
- W2317695215 hasRelatedWork W2002041381 @default.
- W2317695215 hasRelatedWork W2136136116 @default.
- W2317695215 hasRelatedWork W2220371426 @default.
- W2317695215 hasRelatedWork W2317695215 @default.
- W2317695215 hasRelatedWork W2404152533 @default.
- W2317695215 hasRelatedWork W2414620769 @default.
- W2317695215 hasRelatedWork W2421349526 @default.
- W2317695215 isParatext "false" @default.
- W2317695215 isRetracted "false" @default.
- W2317695215 magId "2317695215" @default.
- W2317695215 workType "article" @default.