FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2317702954> ?p ?o ?g. }

• W2317702954 endingPage "97" @default.
• W2317702954 startingPage "87" @default.
• W2317702954 abstract "Seventy-eight melanoma patients and 10 healthy individuals were examined. Follow-up examinations of all melanoma patients were performed regularly every three months. Myeloid-derived suppressor cells (MDSC) were defined as lineage negative (CD3(-), CD19(-), CD56(-)), HLA-DR(-/low), CD11b(+) and CD33(+). Classification of granulocytic (GrMDSC) and monocytic (MoMDSC) subsets was based on the CD15 and CD14 expression, respectively. Unlike the MoMDSC, that were present in 60% of healthy controls and 15% of melanoma patients, the GrMDSC were present in all examined participants, and the melanoma patients were found to have statistically higher frequencies compared with healthy controls. Accordingly, we kept focused on GrMDSC frequencies in relation to the melanoma stages and course of the disease. The GrMDSC values are highest in stage IV melanoma patients, with statistical significance compared with stages IA, IB, IIA and IIB. Patients with progression had statistically higher GrMDSC counts comparing with those with stable disease (P = 0.0079). Patients who had progression-free interval (PFI) < 12 months showed significantly higher GrMDSC values compared with those with PFI > 12 months (P = 0.0333). GrMDSC showed significant negative correlation with PFI intervals (P = 0.0095). The GrMDSC subset was predominant in all our patients. We confirmed that GrMDSC do accumulate early in the peripheral blood of melanoma patients and their frequencies correlate narrowly with the clinical stage and the spread of the disease. The increase in GrMDSC frequencies correlates well with a progressive disease and could be considered a potential predictive biomarker of high-risk melanoma cases that are more likely to have a shorter PFI." @default.
• W2317702954 created "2016-06-24" @default.
• W2317702954 creator A5005031112 @default.
• W2317702954 creator A5005612117 @default.
• W2317702954 creator A5016604472 @default.
• W2317702954 creator A5036225228 @default.
• W2317702954 creator A5037245278 @default.
• W2317702954 creator A5037724535 @default.
• W2317702954 creator A5043332144 @default.
• W2317702954 creator A5050772031 @default.
• W2317702954 creator A5053481583 @default.
• W2317702954 creator A5059160673 @default.
• W2317702954 date "2015-09-21" @default.
• W2317702954 modified "2023-10-17" @default.
• W2317702954 title "A subpopulation that may correspond to granulocytic myeloid-derived suppressor cells reflects the clinical stage and progression of cutaneous melanoma" @default.
• W2317702954 cites W1482307014 @default.
• W2317702954 cites W1526617084 @default.
• W2317702954 cites W1549585090 @default.
• W2317702954 cites W1606003850 @default.
• W2317702954 cites W1612749618 @default.
• W2317702954 cites W1925817305 @default.
• W2317702954 cites W1975191869 @default.
• W2317702954 cites W1989111278 @default.
• W2317702954 cites W1991711981 @default.
• W2317702954 cites W1995232616 @default.
• W2317702954 cites W2000756990 @default.
• W2317702954 cites W2001018971 @default.
• W2317702954 cites W2004150448 @default.
• W2317702954 cites W2006474456 @default.
• W2317702954 cites W2014466662 @default.
• W2317702954 cites W2016685578 @default.
• W2317702954 cites W2031200699 @default.
• W2317702954 cites W2031352878 @default.
• W2317702954 cites W2031968247 @default.
• W2317702954 cites W2038918212 @default.
• W2317702954 cites W2043610206 @default.
• W2317702954 cites W2053829861 @default.
• W2317702954 cites W2054246680 @default.
• W2317702954 cites W2056255115 @default.
• W2317702954 cites W2060672294 @default.
• W2317702954 cites W2060727628 @default.
• W2317702954 cites W2062721793 @default.
• W2317702954 cites W2063874265 @default.
• W2317702954 cites W2064607012 @default.
• W2317702954 cites W2068994108 @default.
• W2317702954 cites W2075326745 @default.
• W2317702954 cites W2079357192 @default.
• W2317702954 cites W2080886891 @default.
• W2317702954 cites W2088067478 @default.
• W2317702954 cites W2101490383 @default.
• W2317702954 cites W2111762872 @default.
• W2317702954 cites W2112227887 @default.
• W2317702954 cites W2117170739 @default.
• W2317702954 cites W2117728670 @default.
• W2317702954 cites W2119077297 @default.
• W2317702954 cites W2120914029 @default.
• W2317702954 cites W2122403898 @default.
• W2317702954 cites W2132132140 @default.
• W2317702954 cites W2134149068 @default.
• W2317702954 cites W2146437446 @default.
• W2317702954 cites W2152677909 @default.
• W2317702954 cites W2154706694 @default.
• W2317702954 cites W2163242247 @default.
• W2317702954 cites W2168205651 @default.
• W2317702954 cites W2239379672 @default.
• W2317702954 doi "https://doi.org/10.1093/intimm/dxv053" @default.
• W2317702954 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4885218" @default.
• W2317702954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26391013" @default.
• W2317702954 hasPublicationYear "2015" @default.
• W2317702954 type Work @default.
• W2317702954 sameAs 2317702954 @default.
• W2317702954 citedByCount "20" @default.
• W2317702954 countsByYear W23177029542015 @default.
• W2317702954 countsByYear W23177029542016 @default.
• W2317702954 countsByYear W23177029542017 @default.
• W2317702954 countsByYear W23177029542018 @default.
• W2317702954 countsByYear W23177029542019 @default.
• W2317702954 countsByYear W23177029542020 @default.
• W2317702954 countsByYear W23177029542021 @default.
• W2317702954 countsByYear W23177029542022 @default.
• W2317702954 countsByYear W23177029542023 @default.
• W2317702954 crossrefType "journal-article" @default.
• W2317702954 hasAuthorship W2317702954A5005031112 @default.
• W2317702954 hasAuthorship W2317702954A5005612117 @default.
• W2317702954 hasAuthorship W2317702954A5016604472 @default.
• W2317702954 hasAuthorship W2317702954A5036225228 @default.
• W2317702954 hasAuthorship W2317702954A5037245278 @default.
• W2317702954 hasAuthorship W2317702954A5037724535 @default.
• W2317702954 hasAuthorship W2317702954A5043332144 @default.
• W2317702954 hasAuthorship W2317702954A5050772031 @default.
• W2317702954 hasAuthorship W2317702954A5053481583 @default.
• W2317702954 hasAuthorship W2317702954A5059160673 @default.
• W2317702954 hasBestOaLocation W23177029541 @default.
• W2317702954 hasConcept C10205521 @default.
• W2317702954 hasConcept C121608353 @default.
• W2317702954 hasConcept C126322002 @default.
• W2317702954 hasConcept C143998085 @default.
• W2317702954 hasConcept C146357865 @default.

• next