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- W2317772484 abstract "Objective: Heart failure (HF) is an increasingly prevalent syndrome, affecting a growing number of people worldwide. Only few epidemiological studies on the prevalence of sleep related breathing disorders in patients with HF are available. No data in this regard are available in Europe. The ProMISeS study, aims at generating a multidisciplinary database containing sleep and clinical data from HF patients referred to the Italian heart failure centers. Methods : At present we have consecutively enrolled 280 HF patients (without acute cardiac decompensation episodes in the last 4 weeks) in whom polysomnography was performed. Methods: At present we have consecutively enrolled 280 HF patients in whom polysomnography was performed. Results: 225 (80%) patients had AHI>5. 152 patients (54%) had mainly OSA, while 73 patients (26%) were conversely affected mostly by CSA. Both OSA and CSA patients were more frequently males (respectively 80% and 92%), in particular male gender was a significant risk factor for CSA (p<0.05). No statistically significant differences were observed when we compared BMI among OSA, CSA (BMI=29 in both group) and patients without SRBD (BMI=28). The prevalence of hypertension was 53% in non SRBD, 55% in CSA and 60% in OSAS. Hypertension could be identified as a major pathogenetic mechanism responsible for HF development in 3.9% of the OSA group while it was not found in CSA patients. Conclusions: Our data provide a clear demonstration of the high prevalence of SRBD in HF patients. Male gender was a risk factor both for central and obstructive sleep apneas, while BMI was not significantly different among group. Interestingly, prevalence of hypertension was higher in OSA group, in which elevated blood pressure might have played a key role also in determining HF appearance." @default.
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- W2317772484 date "2012-09-01" @default.
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- W2317772484 title "344 HYPERTENSION, HEART FAILURE AND SLEEP RELATED BREATHING DISORDERS" @default.
- W2317772484 doi "https://doi.org/10.1097/01.hjh.0000420101.03239.5c" @default.
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