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• W2317791808 abstract "We present an analysis of the evolutionary relationship between genome size (C-value, mass of DNA per haploid nucleus) and developmental rate using observations of limb regeneration in salamanders of the family Plethodontidae. Rates of growth and differentiation of regenerating limbs are reported for 27 plethodontid species whose C-values range from 14 to 76 picograms. A phylogenetic analysis employing Felsenstein's method of independent contrasts indicates that rate of differentiation is inversely proportional to genome size, although we have not identified any statistically significant association between genome size and the growth rate of regenerating tissue. Our results are consistent with an interpretation that genome size may place a limit on the maximum rate of regeneration attainable in plethodontid salamanders. The implications of our findings for the junk DNA, nucleotypic DNA, selfish DNA, and skeletal DNA hypotheses of genome evolution are discussed." @default.
• W2317791808 created "2016-06-24" @default.
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• W2317791808 date "1987-11-01" @default.
• W2317791808 modified "2023-10-12" @default.
• W2317791808 title "DEVELOPMENTAL CORRELATES OF GENOME SIZE IN PLETHODONTID SALAMANDERS AND THEIR IMPLICATIONS FOR GENOME EVOLUTION" @default.
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• W2317791808 doi "https://doi.org/10.1111/j.1558-5646.1987.tb02463.x" @default.
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