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- W2317883472 abstract "Two patients with congenital neutropenia were found to have abnormalities of the immature myeloid cells. These cells were incapable of complete differentiation to a mature stage and also had a substantial reduction in their capacity for cell proliferation. The defect in one patient appeared to be intrinsic to an abnormal cell line, but in the other bone-marrow environmental factors may have contributed to the defect in maturation and proliferation. The surprisingly benign clinical courses may be explained by compensatory defense mechanisms." @default.
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- W2317883472 date "1970-11-12" @default.
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- W2317883472 title "Defective Myelopoiesis in Congenital Neutropenia" @default.
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- W2317883472 doi "https://doi.org/10.1056/nejm197011122832002" @default.
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