Matches in SemOpenAlex for { <https://semopenalex.org/work/W231790614> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W231790614 endingPage "10" @default.
- W231790614 startingPage "6" @default.
- W231790614 abstract "On March 14th of this year, the birthday of Paul Ehrlich, the great German researcher and ‘founder of chemotherapy’, returned for the 150th time. Interestingly, his later colleague Emil von Behring was born one day later in 1854. Both were coworkers in Robert Koch’s laboratory and became Nobel Prize laureates (for their work in immunology), making great contributions to antiinfectious treatments. Emil von Behring’s approach was through the use of immunological agents, while Ehrlich favored an approach of antiinfectious treatment by chemical agents. Through an ingenious concept that was a clear continuation of his early days in research with dyes, he found the first chemotherapeutic agents. From his dye work, he had concluded the following: if there are dyes that one can use to stain cells, why not develop pharmacological agents that, like stains, also attach to a structure in the living pathogen and kill them. He gave these agents the emotionally charged name ‘magic bullets’. This introductory review will initiate a series of papers on the occasion of Ehrlich’s 150th birthday and the ‘World Conference on Dosing of Antiinfectives: Dosing the Magic Bullets’, which is going to be held in Nürnberg, Germany, from September 9 to 11, 2004 (see www.ehrlich2004.org). Apart from the conference topic, this conference will also commemorate a real science giant of the last century and yet a modest human being whom, as Robert Koch put it, ‘one had to like’. This article recalls Ehrlich’s ingenious concepts, including modern syphilis treatment, one-dose treatment (‘therapia magna sterilisans’) of <i>Helicobacter pylori</i> infections and introduction of an arsenic compound, arsenic trioxide, as well as experiments and new exciting data on Congo red, a well-known ‘non-Ehrlich dye’." @default.
- W231790614 created "2016-06-24" @default.
- W231790614 creator A5065255082 @default.
- W231790614 date "2004-01-01" @default.
- W231790614 modified "2023-09-23" @default.
- W231790614 title "The Return of Ehrlich’s ‘Therapia magna sterilisans’ and Other Ehrlich Concepts?" @default.
- W231790614 cites W1977733590 @default.
- W231790614 cites W2002392882 @default.
- W231790614 cites W2045613902 @default.
- W231790614 cites W2053696392 @default.
- W231790614 doi "https://doi.org/10.1159/000077277" @default.
- W231790614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15084798" @default.
- W231790614 hasPublicationYear "2004" @default.
- W231790614 type Work @default.
- W231790614 sameAs 231790614 @default.
- W231790614 citedByCount "19" @default.
- W231790614 countsByYear W2317906142014 @default.
- W231790614 countsByYear W2317906142018 @default.
- W231790614 countsByYear W2317906142021 @default.
- W231790614 crossrefType "journal-article" @default.
- W231790614 hasAuthorship W231790614A5065255082 @default.
- W231790614 hasConcept C121332964 @default.
- W231790614 hasConcept C138885662 @default.
- W231790614 hasConcept C154775046 @default.
- W231790614 hasConcept C2777704519 @default.
- W231790614 hasConcept C41895202 @default.
- W231790614 hasConcept C52119013 @default.
- W231790614 hasConcept C62520636 @default.
- W231790614 hasConcept C71924100 @default.
- W231790614 hasConcept C74916050 @default.
- W231790614 hasConcept C95457728 @default.
- W231790614 hasConceptScore W231790614C121332964 @default.
- W231790614 hasConceptScore W231790614C138885662 @default.
- W231790614 hasConceptScore W231790614C154775046 @default.
- W231790614 hasConceptScore W231790614C2777704519 @default.
- W231790614 hasConceptScore W231790614C41895202 @default.
- W231790614 hasConceptScore W231790614C52119013 @default.
- W231790614 hasConceptScore W231790614C62520636 @default.
- W231790614 hasConceptScore W231790614C71924100 @default.
- W231790614 hasConceptScore W231790614C74916050 @default.
- W231790614 hasConceptScore W231790614C95457728 @default.
- W231790614 hasIssue "1" @default.
- W231790614 hasLocation W2317906141 @default.
- W231790614 hasLocation W2317906142 @default.
- W231790614 hasOpenAccess W231790614 @default.
- W231790614 hasPrimaryLocation W2317906141 @default.
- W231790614 hasRelatedWork W1999274556 @default.
- W231790614 hasRelatedWork W2045140387 @default.
- W231790614 hasRelatedWork W2316977502 @default.
- W231790614 hasRelatedWork W2332569739 @default.
- W231790614 hasRelatedWork W2748952813 @default.
- W231790614 hasRelatedWork W2899084033 @default.
- W231790614 hasRelatedWork W2915517820 @default.
- W231790614 hasRelatedWork W42895856 @default.
- W231790614 hasRelatedWork W583768980 @default.
- W231790614 hasRelatedWork W650993767 @default.
- W231790614 hasVolume "50" @default.
- W231790614 isParatext "false" @default.
- W231790614 isRetracted "false" @default.
- W231790614 magId "231790614" @default.
- W231790614 workType "article" @default.